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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NAT2 All Species: 19.09
Human Site: Y101 Identified Species: 60
UniProt: P11245 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11245 NP_000006.2 290 33542 Y101 Y I P P V N K Y S T G M V H L
Chimpanzee Pan troglodytes XP_519631 290 33543 Y101 Y I P P A N K Y S T G M V H L
Rhesus Macaque Macaca mulatta Q7YRG5 290 33411 Y101 Y I P A A N K Y S T G M I H L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P50295 290 33683 Y101 F N T P A N K Y S S G M I H L
Rat Rattus norvegicus P50298 290 33738 Y101 F N T P A N K Y S S G M I H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508302 289 33116 E99 K V Y S V P E E R Y C E K A S
Chicken Gallus gallus P13913 290 33907 Y101 F N P H E N A Y A T I M T H L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001334322 288 33007 S86 L K E M G Y K S T I L S G R V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.9 89.3 N.A. N.A. 74.8 73.7 N.A. 52 56.5 N.A. 41 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.5 92.7 N.A. N.A. 86.9 85.5 N.A. 69.6 72 N.A. 59.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 80 N.A. N.A. 60 60 N.A. 6.6 46.6 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 86.6 N.A. N.A. 80 80 N.A. 20 60 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 50 0 13 0 13 0 0 0 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 13 0 13 0 13 13 0 0 0 13 0 0 0 % E
% Phe: 38 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 13 0 0 0 0 0 63 0 13 0 0 % G
% His: 0 0 0 13 0 0 0 0 0 0 0 0 0 75 0 % H
% Ile: 0 38 0 0 0 0 0 0 0 13 13 0 38 0 0 % I
% Lys: 13 13 0 0 0 0 75 0 0 0 0 0 13 0 0 % K
% Leu: 13 0 0 0 0 0 0 0 0 0 13 0 0 0 75 % L
% Met: 0 0 0 13 0 0 0 0 0 0 0 75 0 0 0 % M
% Asn: 0 38 0 0 0 75 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 50 50 0 13 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 13 0 0 0 0 13 0 % R
% Ser: 0 0 0 13 0 0 0 13 63 25 0 13 0 0 13 % S
% Thr: 0 0 25 0 0 0 0 0 13 50 0 0 13 0 0 % T
% Val: 0 13 0 0 25 0 0 0 0 0 0 0 25 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 38 0 13 0 0 13 0 75 0 13 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _