KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTB
All Species:
14.85
Human Site:
S1381
Identified Species:
40.83
UniProt:
P11277
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11277
NP_000338.3
2137
246468
S1381
H
L
S
A
A
R
S
S
D
L
R
L
Q
T
H
Chimpanzee
Pan troglodytes
XP_001170737
2137
246560
S1381
H
L
S
A
A
R
S
S
D
L
R
L
Q
T
H
Rhesus Macaque
Macaca mulatta
XP_001114804
2364
274624
A1382
R
L
F
D
A
N
K
A
E
L
F
T
Q
S
C
Dog
Lupus familis
XP_547856
2138
246498
S1381
H
L
S
A
A
R
S
S
Y
L
R
S
Q
T
H
Cat
Felis silvestris
Mouse
Mus musculus
P15508
2128
245232
S1373
Q
L
S
A
A
R
S
S
D
L
R
L
Q
T
H
Rat
Rattus norvegicus
Q9QWN8
2388
271046
A1385
S
L
F
D
A
N
R
A
E
L
F
A
Q
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P07751
2477
285345
Q1665
K
L
K
E
A
N
K
Q
Q
N
F
N
T
G
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571600
2357
272809
S1390
L
L
F
D
A
N
R
S
E
L
F
D
Q
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q00963
2291
265721
E1382
M
L
F
D
A
N
R
E
V
L
V
Q
Q
T
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
56.1
91.3
N.A.
90.4
49.4
N.A.
N.A.
23.6
N.A.
59
N.A.
47
N.A.
N.A.
N.A.
Protein Similarity:
100
99.9
71.9
95.4
N.A.
95
66
N.A.
N.A.
43.6
N.A.
73.4
N.A.
64.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
86.6
N.A.
93.3
26.6
N.A.
N.A.
13.3
N.A.
33.3
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
86.6
N.A.
93.3
46.6
N.A.
N.A.
13.3
N.A.
46.6
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
45
100
0
0
23
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% C
% Asp:
0
0
0
45
0
0
0
0
34
0
0
12
0
0
0
% D
% Glu:
0
0
0
12
0
0
0
12
34
0
0
0
0
0
0
% E
% Phe:
0
0
45
0
0
0
0
0
0
0
45
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% G
% His:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
45
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% I
% Lys:
12
0
12
0
0
0
23
0
0
0
0
0
0
0
0
% K
% Leu:
12
100
0
0
0
0
0
0
0
89
0
34
0
0
12
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
56
0
0
0
12
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
12
12
0
0
12
89
0
0
% Q
% Arg:
12
0
0
0
0
45
34
0
0
0
45
0
0
0
0
% R
% Ser:
12
0
45
0
0
0
45
56
0
0
0
12
0
34
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
12
12
56
0
% T
% Val:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _