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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPTB All Species: 27.27
Human Site: S767 Identified Species: 75
UniProt: P11277 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11277 NP_000338.3 2137 246468 S767 Q D A H R L L S G E D V G Q D
Chimpanzee Pan troglodytes XP_001170737 2137 246560 S767 Q D A H R L L S G E D V G Q D
Rhesus Macaque Macaca mulatta XP_001114804 2364 274624 S768 L D I L K I V S S S D V G H D
Dog Lupus familis XP_547856 2138 246498 S767 Q D A H R L L S G E D V G Q D
Cat Felis silvestris
Mouse Mus musculus P15508 2128 245232 S759 Q D A H R L L S G E D V G Q D
Rat Rattus norvegicus Q9QWN8 2388 271046 S771 V D A L R L V S S P E V G H D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P07751 2477 285345 S982 L Y D Y Q E K S P R E V T M K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_571600 2357 272809 S775 V D A M R Q M S S D D V G H D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00963 2291 265721 S765 L D T L R I V S S E D V G R D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 56.1 91.3 N.A. 90.4 49.4 N.A. N.A. 23.6 N.A. 59 N.A. 47 N.A. N.A. N.A.
Protein Similarity: 100 99.9 71.9 95.4 N.A. 95 66 N.A. N.A. 43.6 N.A. 73.4 N.A. 64.3 N.A. N.A. N.A.
P-Site Identity: 100 100 40 100 N.A. 100 53.3 N.A. N.A. 13.3 N.A. 53.3 N.A. 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 60 100 N.A. 100 66.6 N.A. N.A. 33.3 N.A. 66.6 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 89 12 0 0 0 0 0 0 12 78 0 0 0 89 % D
% Glu: 0 0 0 0 0 12 0 0 0 56 23 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 45 0 0 0 89 0 0 % G
% His: 0 0 0 45 0 0 0 0 0 0 0 0 0 34 0 % H
% Ile: 0 0 12 0 0 23 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 12 0 12 0 0 0 0 0 0 0 12 % K
% Leu: 34 0 0 34 0 56 45 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 12 0 0 12 0 0 0 0 0 0 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 12 12 0 0 0 0 0 % P
% Gln: 45 0 0 0 12 12 0 0 0 0 0 0 0 45 0 % Q
% Arg: 0 0 0 0 78 0 0 0 0 12 0 0 0 12 0 % R
% Ser: 0 0 0 0 0 0 0 100 45 12 0 0 0 0 0 % S
% Thr: 0 0 12 0 0 0 0 0 0 0 0 0 12 0 0 % T
% Val: 23 0 0 0 0 0 34 0 0 0 0 100 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 12 0 12 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _