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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMP1
All Species:
18.48
Human Site:
S141
Identified Species:
40.67
UniProt:
P11279
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11279
NP_005552.3
417
44882
S141
K
E
I
K
T
V
E
S
I
T
D
I
R
A
D
Chimpanzee
Pan troglodytes
XP_001144542
375
40516
C113
D
I
D
K
K
Y
R
C
V
S
G
T
Q
V
H
Rhesus Macaque
Macaca mulatta
XP_001087801
416
44772
S140
K
E
I
K
T
V
E
S
I
T
D
I
R
A
D
Dog
Lupus familis
XP_534193
413
44257
S137
K
E
T
K
T
V
E
S
A
T
D
I
R
A
D
Cat
Felis silvestris
Mouse
Mus musculus
P11438
406
43847
S135
K
E
I
Y
T
M
D
S
T
T
D
I
K
A
D
Rat
Rattus norvegicus
P14562
407
43951
S136
K
G
P
D
T
V
D
S
T
T
D
I
K
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510101
454
50017
E182
G
Q
V
L
S
V
F
E
F
R
Y
A
R
I
P
Chicken
Gallus gallus
P05300
414
44651
T138
V
I
Q
A
R
I
G
T
E
Y
R
C
I
N
S
Frog
Xenopus laevis
NP_001087042
417
45343
T141
N
G
T
K
T
V
S
T
N
K
T
A
V
L
A
Zebra Danio
Brachydanio rerio
NP_955996
411
43489
S136
Q
S
V
M
A
S
V
S
E
L
M
S
A
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789418
489
51961
I206
M
Y
S
A
T
L
P
I
N
T
F
K
V
K
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.2
96.6
80.3
N.A.
67.1
65.4
N.A.
32.1
52
44.5
42.6
N.A.
N.A.
N.A.
N.A.
25.9
Protein Similarity:
100
89.4
97.5
89.2
N.A.
78.1
77.4
N.A.
50.8
69
62.5
62.8
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
100
6.6
100
86.6
N.A.
66.6
60
N.A.
13.3
0
20
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
26.6
100
86.6
N.A.
86.6
73.3
N.A.
33.3
13.3
26.6
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
10
0
0
0
10
0
0
19
10
46
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% C
% Asp:
10
0
10
10
0
0
19
0
0
0
46
0
0
0
55
% D
% Glu:
0
37
0
0
0
0
28
10
19
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
10
0
10
0
0
0
0
% F
% Gly:
10
19
0
0
0
0
10
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
19
28
0
0
10
0
10
19
0
0
46
10
10
0
% I
% Lys:
46
0
0
46
10
0
0
0
0
10
0
10
19
10
0
% K
% Leu:
0
0
0
10
0
10
0
0
0
10
0
0
0
10
10
% L
% Met:
10
0
0
10
0
10
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
19
0
0
0
0
10
0
% N
% Pro:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
10
% P
% Gln:
10
10
10
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
10
0
10
0
0
10
10
0
37
10
0
% R
% Ser:
0
10
10
0
10
10
10
55
0
10
0
10
0
0
10
% S
% Thr:
0
0
19
0
64
0
0
19
19
55
10
10
0
0
0
% T
% Val:
10
0
19
0
0
55
10
0
10
0
0
0
19
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
10
0
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _