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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMP1
All Species:
8.79
Human Site:
T251
Identified Species:
19.33
UniProt:
P11279
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11279
NP_005552.3
417
44882
T251
Y
E
R
K
D
N
T
T
V
T
R
L
L
N
I
Chimpanzee
Pan troglodytes
XP_001144542
375
40516
A223
I
N
P
N
K
T
S
A
S
G
S
C
G
A
H
Rhesus Macaque
Macaca mulatta
XP_001087801
416
44772
T250
Y
E
R
K
D
N
T
T
V
T
R
L
L
N
I
Dog
Lupus familis
XP_534193
413
44257
T247
Y
K
K
K
D
N
T
T
V
V
K
V
V
S
I
Cat
Felis silvestris
Mouse
Mus musculus
P11438
406
43847
R245
K
D
N
K
T
V
T
R
A
F
N
I
S
P
N
Rat
Rattus norvegicus
P14562
407
43951
R246
K
D
N
T
T
V
T
R
A
F
N
I
N
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510101
454
50017
V292
L
N
V
T
Q
N
K
V
N
S
V
I
N
I
N
Chicken
Gallus gallus
P05300
414
44651
M248
Y
V
K
K
D
E
K
M
G
L
D
L
L
N
F
Frog
Xenopus laevis
NP_001087042
417
45343
K251
T
Y
T
T
K
D
G
K
N
G
S
Y
V
F
N
Zebra Danio
Brachydanio rerio
NP_955996
411
43489
Q246
T
H
T
T
T
Q
N
Q
S
V
S
E
L
M
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789418
489
51961
K316
S
Y
K
T
S
K
D
K
V
N
V
T
T
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.2
96.6
80.3
N.A.
67.1
65.4
N.A.
32.1
52
44.5
42.6
N.A.
N.A.
N.A.
N.A.
25.9
Protein Similarity:
100
89.4
97.5
89.2
N.A.
78.1
77.4
N.A.
50.8
69
62.5
62.8
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
100
0
100
53.3
N.A.
13.3
6.6
N.A.
6.6
40
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
93.3
N.A.
26.6
20
N.A.
20
46.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
19
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
19
0
0
37
10
10
0
0
0
10
0
0
0
0
% D
% Glu:
0
19
0
0
0
10
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
19
0
0
0
10
10
% F
% Gly:
0
0
0
0
0
0
10
0
10
19
0
0
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
28
0
10
28
% I
% Lys:
19
10
28
46
19
10
19
19
0
0
10
0
0
0
10
% K
% Leu:
10
0
0
0
0
0
0
0
0
10
0
28
37
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% M
% Asn:
0
19
19
10
0
37
10
0
19
10
19
0
19
28
37
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
19
0
% P
% Gln:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
0
0
0
0
19
0
0
19
0
0
0
0
% R
% Ser:
10
0
0
0
10
0
10
0
19
10
28
0
10
10
10
% S
% Thr:
19
0
19
46
28
10
46
28
0
19
0
10
10
0
0
% T
% Val:
0
10
10
0
0
19
0
10
37
19
19
10
19
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
37
19
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _