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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAMP1
All Species:
19.7
Human Site:
Y178
Identified Species:
43.33
UniProt:
P11279
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11279
NP_005552.3
417
44882
Y178
H
D
A
T
I
Q
A
Y
L
S
N
S
S
F
S
Chimpanzee
Pan troglodytes
XP_001144542
375
40516
E150
S
R
G
E
T
R
C
E
Q
D
R
P
S
P
T
Rhesus Macaque
Macaca mulatta
XP_001087801
416
44772
Y177
H
D
A
T
I
Q
A
Y
L
S
N
S
S
F
S
Dog
Lupus familis
XP_534193
413
44257
Y174
H
D
V
T
I
Q
A
Y
L
A
N
S
N
F
S
Cat
Felis silvestris
Mouse
Mus musculus
P11438
406
43847
Y172
R
D
A
T
I
Q
A
Y
L
S
S
G
N
F
S
Rat
Rattus norvegicus
P14562
407
43951
Y173
W
D
A
T
I
Q
A
Y
L
P
S
S
N
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510101
454
50017
F219
W
E
T
V
V
Q
A
F
I
Q
N
G
T
I
S
Chicken
Gallus gallus
P05300
414
44651
K175
N
D
T
F
S
A
N
K
T
E
C
R
E
D
M
Frog
Xenopus laevis
NP_001087042
417
45343
A178
F
H
D
I
R
L
E
A
Y
L
K
Q
S
N
F
Zebra Danio
Brachydanio rerio
NP_955996
411
43489
Y173
S
G
V
Q
M
E
A
Y
M
S
S
A
N
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789418
489
51961
A243
S
K
V
K
I
Q
T
A
D
I
D
N
N
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.2
96.6
80.3
N.A.
67.1
65.4
N.A.
32.1
52
44.5
42.6
N.A.
N.A.
N.A.
N.A.
25.9
Protein Similarity:
100
89.4
97.5
89.2
N.A.
78.1
77.4
N.A.
50.8
69
62.5
62.8
N.A.
N.A.
N.A.
N.A.
41.5
P-Site Identity:
100
6.6
100
80
N.A.
73.3
73.3
N.A.
26.6
6.6
6.6
26.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
100
93.3
N.A.
86.6
86.6
N.A.
60
13.3
6.6
66.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
37
0
0
10
64
19
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% C
% Asp:
0
55
10
0
0
0
0
0
10
10
10
0
0
10
0
% D
% Glu:
0
10
0
10
0
10
10
10
0
10
0
0
10
0
0
% E
% Phe:
10
0
0
10
0
0
0
10
0
0
0
0
0
46
19
% F
% Gly:
0
10
10
0
0
0
0
0
0
0
0
19
0
0
0
% G
% His:
28
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
55
0
0
0
10
10
0
0
0
10
0
% I
% Lys:
0
10
0
10
0
0
0
10
0
0
10
0
0
10
0
% K
% Leu:
0
0
0
0
0
10
0
0
46
10
0
0
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
10
0
0
0
37
10
46
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% P
% Gln:
0
0
0
10
0
64
0
0
10
10
0
10
0
0
0
% Q
% Arg:
10
10
0
0
10
10
0
0
0
0
10
10
0
0
0
% R
% Ser:
28
0
0
0
10
0
0
0
0
37
28
37
37
0
64
% S
% Thr:
0
0
19
46
10
0
10
0
10
0
0
0
10
0
10
% T
% Val:
0
0
28
10
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _