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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERG All Species: 20.61
Human Site: S43 Identified Species: 45.33
UniProt: P11308 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11308 NP_001129626.1 486 54608 S43 A K T E M T A S S S S D Y G Q
Chimpanzee Pan troglodytes XP_514895 489 54932 S46 A K T E M T A S S S S D Y G Q
Rhesus Macaque Macaca mulatta XP_001082130 489 54996 S46 A K T E M T A S S S S D Y G Q
Dog Lupus familis XP_857284 482 54468 G43 A S G S P D Y G Q P H K I N P
Cat Felis silvestris
Mouse Mus musculus P81270 486 54596 S43 A K T E M T A S S S S D Y G Q
Rat Rattus norvegicus P41156 441 50404 T12 V D L K P T L T I I K T E K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509996 570 64208 S127 T K A E M T A S S S S E Y G Q
Chicken Gallus gallus Q90837 478 53895 Q43 S S S S E Y G Q T S K M S P R
Frog Xenopus laevis P41157 453 50997 S26 F D S A Y G A S S H L S K A D
Zebra Danio Brachydanio rerio A3FEM2 235 26324
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29774 490 52037 S48 T S Y R F H Q S T F E Q L K Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.9 97.1 67.4 N.A. 97.1 24.8 N.A. 79.4 93.4 61.7 27.7 N.A. 35.5 N.A. N.A. N.A.
Protein Similarity: 100 97.5 97.7 77.3 N.A. 98.5 39 N.A. 81.5 95.4 72.8 35.5 N.A. 48.5 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 6.6 N.A. 80 6.6 20 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 100 20 N.A. 86.6 33.3 26.6 0 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 46 0 10 10 0 0 55 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 0 0 10 0 0 0 0 0 37 0 0 10 % D
% Glu: 0 0 0 46 10 0 0 0 0 0 10 10 10 0 0 % E
% Phe: 10 0 0 0 10 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 10 10 10 0 0 0 0 0 46 0 % G
% His: 0 0 0 0 0 10 0 0 0 10 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 10 0 0 10 0 0 % I
% Lys: 0 46 0 10 0 0 0 0 0 0 19 10 10 19 0 % K
% Leu: 0 0 10 0 0 0 10 0 0 0 10 0 10 0 0 % L
% Met: 0 0 0 0 46 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 19 0 0 0 0 10 0 0 0 10 10 % P
% Gln: 0 0 0 0 0 0 10 10 10 0 0 10 0 0 55 % Q
% Arg: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 10 28 19 19 0 0 0 64 55 55 46 10 10 0 0 % S
% Thr: 19 0 37 0 0 55 0 10 19 0 0 10 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 10 10 10 0 0 0 0 0 46 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _