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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERG All Species: 23.33
Human Site: Y244 Identified Species: 51.33
UniProt: P11308 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11308 NP_001129626.1 486 54608 Y244 I F P N T S V Y P E A T Q R I
Chimpanzee Pan troglodytes XP_514895 489 54932 Y247 I F P N T S V Y P E A T Q R I
Rhesus Macaque Macaca mulatta XP_001082130 489 54996 Y247 I F P N T S V Y P E A T Q R I
Dog Lupus familis XP_857284 482 54468 L237 S H P P T S I L P Q R H Q S V
Cat Felis silvestris
Mouse Mus musculus P81270 486 54596 Y244 I F P N T S V Y P E A T Q R I
Rat Rattus norvegicus P41156 441 50404 P206 L K Y E N D Y P S V I L R D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509996 570 64208 Y328 I F P N T S V Y P E P T Q R I
Chicken Gallus gallus Q90837 478 53895 Y237 I F P N T S V Y P E A T Q R I
Frog Xenopus laevis P41157 453 50997 P220 R L T A K E D P S Y E A V R R
Zebra Danio Brachydanio rerio A3FEM2 235 26324
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29774 490 52037 S243 G S K S S N T S G T G G G A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.9 97.1 67.4 N.A. 97.1 24.8 N.A. 79.4 93.4 61.7 27.7 N.A. 35.5 N.A. N.A. N.A.
Protein Similarity: 100 97.5 97.7 77.3 N.A. 98.5 39 N.A. 81.5 95.4 72.8 35.5 N.A. 48.5 N.A. N.A. N.A.
P-Site Identity: 100 100 100 33.3 N.A. 100 0 N.A. 93.3 100 6.6 0 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 53.3 N.A. 100 13.3 N.A. 93.3 100 6.6 0 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 46 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 10 0 0 0 0 0 0 10 0 % D
% Glu: 0 0 0 10 0 10 0 0 0 55 10 0 0 0 0 % E
% Phe: 0 55 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 10 0 10 10 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 55 0 0 0 0 0 10 0 0 0 10 0 0 0 55 % I
% Lys: 0 10 10 0 10 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 0 0 0 0 10 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 55 10 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 64 10 0 0 0 19 64 0 10 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 64 0 0 % Q
% Arg: 10 0 0 0 0 0 0 0 0 0 10 0 10 64 10 % R
% Ser: 10 10 0 10 10 64 0 10 19 0 0 0 0 10 10 % S
% Thr: 0 0 10 0 64 0 10 0 0 10 0 55 0 0 0 % T
% Val: 0 0 0 0 0 0 55 0 0 10 0 0 10 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 10 55 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _