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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACADM
All Species:
42.73
Human Site:
Y73
Identified Species:
78.33
UniProt:
P11310
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11310
NP_000007.1
421
46588
Y73
E
Y
D
K
T
G
E
Y
P
V
P
L
I
R
R
Chimpanzee
Pan troglodytes
A5A6I0
421
46589
Y73
E
Y
D
K
T
G
E
Y
P
V
P
L
I
R
R
Rhesus Macaque
Macaca mulatta
XP_001101274
421
46579
Y73
E
Y
D
K
T
G
E
Y
P
V
P
L
I
R
R
Dog
Lupus familis
XP_547328
444
49447
Y96
E
Y
D
K
T
G
E
Y
P
V
P
L
I
K
R
Cat
Felis silvestris
Mouse
Mus musculus
P45952
421
46463
Y73
E
Y
D
K
S
G
E
Y
P
F
P
L
I
K
R
Rat
Rattus norvegicus
P08503
421
46537
Y73
D
Y
D
K
S
G
E
Y
P
F
P
L
I
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506493
476
52130
Y116
E
Y
D
K
S
G
E
Y
P
V
P
L
I
K
R
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001087662
422
46209
Y74
H
Y
D
K
T
G
E
Y
P
V
P
L
I
K
R
Zebra Danio
Brachydanio rerio
NP_998254
424
46128
Y76
S
Y
D
R
S
G
E
Y
P
F
P
L
I
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSA3
419
45853
Y69
Q
Y
D
K
S
G
E
Y
P
W
P
I
I
K
K
Honey Bee
Apis mellifera
XP_392111
417
46502
Y68
E
Y
D
K
N
G
K
Y
P
W
D
I
I
K
K
Nematode Worm
Caenorhab. elegans
Q22347
417
44800
E66
E
S
G
E
F
P
W
E
I
V
R
Q
A
H
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWG0
409
44755
D66
K
T
N
S
F
P
K
D
V
N
L
W
K
L
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.9
84.9
N.A.
87.8
86.4
N.A.
76.4
N.A.
81
79.2
N.A.
67.9
63.4
59.1
N.A.
Protein Similarity:
100
99.7
99
89.6
N.A.
94.7
94
N.A.
84.8
N.A.
91.4
88.2
N.A.
80.7
78.3
74.5
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
73.3
N.A.
86.6
N.A.
86.6
66.6
N.A.
60
53.3
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
N.A.
93.3
86.6
N.A.
93.3
80
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
52.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
85
0
0
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
62
0
0
8
0
0
77
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
16
0
0
0
0
24
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
85
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
0
16
85
0
0
% I
% Lys:
8
0
0
77
0
0
16
0
0
0
0
0
8
62
16
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
8
70
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
16
0
0
85
0
77
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
8
0
0
24
70
% R
% Ser:
8
8
0
8
39
0
0
0
0
0
0
0
0
0
8
% S
% Thr:
0
8
0
0
39
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
54
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
16
0
8
0
0
0
% W
% Tyr:
0
85
0
0
0
0
0
85
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _