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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
G6PD
All Species:
40.3
Human Site:
S106
Identified Species:
63.33
UniProt:
P11413
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11413
NP_000393.4
515
59257
S106
E
D
F
F
A
R
N
S
Y
V
A
G
Q
Y
D
Chimpanzee
Pan troglodytes
XP_001146640
398
44780
G71
F
I
I
M
G
A
S
G
D
L
A
K
K
K
I
Rhesus Macaque
Macaca mulatta
XP_001095273
515
59249
S106
E
D
F
F
A
R
N
S
Y
V
A
G
Q
Y
D
Dog
Lupus familis
XP_538209
545
62703
S136
E
E
F
F
A
R
N
S
Y
V
A
G
Q
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q00612
515
59244
S106
E
E
F
F
A
R
N
S
Y
V
A
G
Q
Y
D
Rat
Rattus norvegicus
P05370
515
59357
S106
E
E
F
F
A
R
N
S
Y
V
A
G
Q
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505636
515
59203
S106
E
E
F
F
A
R
N
S
Y
V
A
G
Q
Y
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080019
518
59674
S109
D
T
F
F
K
R
N
S
Y
I
S
G
Q
Y
S
Zebra Danio
Brachydanio rerio
XP_699168
523
59677
S114
A
A
F
F
S
R
N
S
Y
I
S
G
K
Y
V
Tiger Blowfish
Takifugu rubipres
P54996
530
60451
S121
S
A
F
F
S
R
N
S
Y
I
S
G
N
Y
T
Fruit Fly
Dros. melanogaster
P12646
524
60412
E110
E
E
F
W
A
L
N
E
Y
V
S
G
R
Y
D
Honey Bee
Apis mellifera
XP_001121185
518
60246
Y110
E
E
F
W
K
L
N
Y
Y
M
A
G
Q
Y
D
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
S108
D
D
F
I
K
K
C
S
Y
V
Q
G
Q
Y
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJI5
515
59098
Q106
E
A
L
S
K
F
L
Q
L
I
K
Y
V
S
G
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
R105
D
E
G
F
D
E
L
R
T
Q
I
E
K
F
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.9
99
87.8
N.A.
93.7
93.7
N.A.
90.2
N.A.
77.2
75.3
74.3
61.2
63.7
58.8
N.A.
Protein Similarity:
100
69.1
99.6
91.5
N.A.
97
96.6
N.A.
96.1
N.A.
89.7
85.8
82.6
74
76.8
74.9
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
60
53.3
53.3
60
60
60
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
100
100
N.A.
100
N.A.
80
80
73.3
86.6
80
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.2
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.5
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
20
0
0
47
7
0
0
0
0
54
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
20
20
0
0
7
0
0
0
7
0
0
0
0
0
60
% D
% Glu:
60
47
0
0
0
7
0
7
0
0
0
7
0
0
7
% E
% Phe:
7
0
80
67
0
7
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
0
7
0
7
0
0
7
0
0
0
80
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
7
7
0
0
0
0
0
27
7
0
0
0
7
% I
% Lys:
0
0
0
0
27
7
0
0
0
0
7
7
20
7
0
% K
% Leu:
0
0
7
0
0
14
14
0
7
7
0
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
74
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
7
0
7
7
0
60
0
0
% Q
% Arg:
0
0
0
0
0
60
0
7
0
0
0
0
7
0
0
% R
% Ser:
7
0
0
7
14
0
7
67
0
0
27
0
0
7
7
% S
% Thr:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
7
% T
% Val:
0
0
0
0
0
0
0
0
0
54
0
0
7
0
7
% V
% Trp:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
80
0
0
7
0
80
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _