Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: G6PD All Species: 30.3
Human Site: S117 Identified Species: 47.62
UniProt: P11413 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11413 NP_000393.4 515 59257 S117 G Q Y D D A A S Y Q R L N S H
Chimpanzee Pan troglodytes XP_001146640 398 44780 I82 K K K I Y P T I W W L F R D G
Rhesus Macaque Macaca mulatta XP_001095273 515 59249 S117 G Q Y D E A A S Y Q R L N S H
Dog Lupus familis XP_538209 545 62703 S147 G Q Y D D V A S Y E R L H S H
Cat Felis silvestris
Mouse Mus musculus Q00612 515 59244 S117 G Q Y D D A A S Y K H L N S H
Rat Rattus norvegicus P05370 515 59357 S117 G Q Y D D P A S Y K H L N S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505636 515 59203 S117 G Q Y D S R A S F E Q L N T H
Chicken Gallus gallus
Frog Xenopus laevis NP_001080019 518 59674 S120 G Q Y S D A A S F Q N L N Q H
Zebra Danio Brachydanio rerio XP_699168 523 59677 S125 G K Y V E E S S F S D L N T H
Tiger Blowfish Takifugu rubipres P54996 530 60451 S132 G N Y T A G G S F S E L N A H
Fruit Fly Dros. melanogaster P12646 524 60412 G121 G R Y D G R T G F E L L N Q Q
Honey Bee Apis mellifera XP_001121185 518 60246 G121 G Q Y D S Q K G F E M L N N E
Nematode Worm Caenorhab. elegans Q27464 522 60197 G119 G Q Y D T S E G F Q R L Q S S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJI5 515 59098 A117 Y V S G P Y D A E E G F Q R L
Baker's Yeast Sacchar. cerevisiae P11412 505 57503 N116 E K F E K S A N V D V P H R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.9 99 87.8 N.A. 93.7 93.7 N.A. 90.2 N.A. 77.2 75.3 74.3 61.2 63.7 58.8 N.A.
Protein Similarity: 100 69.1 99.6 91.5 N.A. 97 96.6 N.A. 96.1 N.A. 89.7 85.8 82.6 74 76.8 74.9 N.A.
P-Site Identity: 100 0 93.3 80 N.A. 86.6 80 N.A. 60 N.A. 73.3 40 40 33.3 40 53.3 N.A.
P-Site Similarity: 100 13.3 100 93.3 N.A. 93.3 86.6 N.A. 86.6 N.A. 80 73.3 53.3 53.3 60 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 52.2 46.4 N.A.
Protein Similarity: N.A. N.A. N.A. 68.5 63.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 27 54 7 0 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 60 34 0 7 0 0 7 7 0 0 7 0 % D
% Glu: 7 0 0 7 14 7 7 0 7 34 7 0 0 0 7 % E
% Phe: 0 0 7 0 0 0 0 0 47 0 0 14 0 0 0 % F
% Gly: 80 0 0 7 7 7 7 20 0 0 7 0 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 14 0 14 0 60 % H
% Ile: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % I
% Lys: 7 20 7 0 7 0 7 0 0 14 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 14 80 0 0 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 7 0 0 7 0 67 7 0 % N
% Pro: 0 0 0 0 7 14 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 60 0 0 0 7 0 0 0 27 7 0 14 14 7 % Q
% Arg: 0 7 0 0 0 14 0 0 0 0 27 0 7 14 0 % R
% Ser: 0 0 7 7 14 14 7 60 0 14 0 0 0 40 7 % S
% Thr: 0 0 0 7 7 0 14 0 0 0 0 0 0 14 0 % T
% Val: 0 7 0 7 0 7 0 0 7 0 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % W
% Tyr: 7 0 80 0 7 7 0 0 34 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _