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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: G6PD All Species: 25.45
Human Site: S84 Identified Species: 40
UniProt: P11413 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11413 NP_000393.4 515 59257 S84 V A D I R K Q S E P F F K A T
Chimpanzee Pan troglodytes XP_001146640 398 44780 E49 V C G I L R E E L F Q G D A F
Rhesus Macaque Macaca mulatta XP_001095273 515 59249 S84 V A D I R K Q S E P F F K A T
Dog Lupus familis XP_538209 545 62703 S114 V A D I R K Q S E P F F K A T
Cat Felis silvestris
Mouse Mus musculus Q00612 515 59244 S84 V D D I R K Q S E P F F K A T
Rat Rattus norvegicus P05370 515 59357 S84 V D D I R K Q S E P F F K V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505636 515 59203 S84 V A D I R K Q S E P Y F K V T
Chicken Gallus gallus
Frog Xenopus laevis NP_001080019 518 59674 S87 V Q D I K K Q S E P Y F K V S
Zebra Danio Brachydanio rerio XP_699168 523 59677 C92 V D A I R I A C M P Y M K V V
Tiger Blowfish Takifugu rubipres P54996 530 60451 C99 V D A I R T S C M P Y L K V T
Fruit Fly Dros. melanogaster P12646 524 60412 C88 V D S I K E Q C L P Y M K V Q
Honey Bee Apis mellifera XP_001121185 518 60246 C88 V N Q L R A K C H P Y M K V K
Nematode Worm Caenorhab. elegans Q27464 522 60197 F86 V F K L R E S F E K N C K V R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJI5 515 59098 R84 S D E E L R D R I R G Y L V D
Baker's Yeast Sacchar. cerevisiae P11412 505 57503 Q83 A D D S K V E Q F F K M V S Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.9 99 87.8 N.A. 93.7 93.7 N.A. 90.2 N.A. 77.2 75.3 74.3 61.2 63.7 58.8 N.A.
Protein Similarity: 100 69.1 99.6 91.5 N.A. 97 96.6 N.A. 96.1 N.A. 89.7 85.8 82.6 74 76.8 74.9 N.A.
P-Site Identity: 100 20 100 100 N.A. 93.3 86.6 N.A. 86.6 N.A. 66.6 33.3 40 33.3 26.6 26.6 N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 93.3 86.6 N.A. 93.3 N.A. 86.6 40 46.6 53.3 46.6 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 52.2 46.4 N.A.
Protein Similarity: N.A. N.A. N.A. 68.5 63.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 27 14 0 0 7 7 0 0 0 0 0 0 34 0 % A
% Cys: 0 7 0 0 0 0 0 27 0 0 0 7 0 0 0 % C
% Asp: 0 47 54 0 0 0 7 0 0 0 0 0 7 0 7 % D
% Glu: 0 0 7 7 0 14 14 7 54 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 7 7 14 34 47 0 0 7 % F
% Gly: 0 0 7 0 0 0 0 0 0 0 7 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 74 0 7 0 0 7 0 0 0 0 0 0 % I
% Lys: 0 0 7 0 20 47 7 0 0 7 7 0 80 0 7 % K
% Leu: 0 0 0 14 14 0 0 0 14 0 0 7 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 14 0 0 27 0 0 0 % M
% Asn: 0 7 0 0 0 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 74 0 0 0 0 0 % P
% Gln: 0 7 7 0 0 0 54 7 0 0 7 0 0 0 7 % Q
% Arg: 0 0 0 0 67 14 0 7 0 7 0 0 0 0 7 % R
% Ser: 7 0 7 7 0 0 14 47 0 0 0 0 0 7 7 % S
% Thr: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 47 % T
% Val: 87 0 0 0 0 7 0 0 0 0 0 0 7 60 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 40 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _