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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
G6PD
All Species:
57.27
Human Site:
Y249
Identified Species:
90
UniProt:
P11413
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11413
NP_000393.4
515
59257
Y249
G
T
E
G
R
G
G
Y
F
D
E
F
G
I
I
Chimpanzee
Pan troglodytes
XP_001146640
398
44780
Q191
I
H
E
S
C
M
S
Q
I
R
G
W
N
R
I
Rhesus Macaque
Macaca mulatta
XP_001095273
515
59249
Y249
G
T
E
G
R
G
G
Y
F
D
E
F
G
I
I
Dog
Lupus familis
XP_538209
545
62703
Y279
G
T
E
G
R
G
G
Y
F
D
E
F
G
I
I
Cat
Felis silvestris
Mouse
Mus musculus
Q00612
515
59244
Y249
G
T
E
G
R
G
G
Y
F
D
E
F
G
I
I
Rat
Rattus norvegicus
P05370
515
59357
Y249
G
T
E
G
R
G
G
Y
F
D
E
F
G
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505636
515
59203
Y249
G
T
E
G
R
G
G
Y
F
D
E
F
G
I
I
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080019
518
59674
Y252
G
T
Q
G
R
G
G
Y
F
D
E
F
G
I
I
Zebra Danio
Brachydanio rerio
XP_699168
523
59677
Y257
G
T
Q
G
R
G
G
Y
F
D
D
F
G
I
I
Tiger Blowfish
Takifugu rubipres
P54996
530
60451
Y264
G
T
Q
G
R
G
G
Y
F
D
D
F
G
I
I
Fruit Fly
Dros. melanogaster
P12646
524
60412
Y253
G
T
Q
G
R
G
G
Y
F
D
E
F
G
I
I
Honey Bee
Apis mellifera
XP_001121185
518
60246
Y254
G
T
Q
G
R
G
G
Y
F
D
E
F
G
I
I
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
Y255
G
T
G
G
R
A
G
Y
F
D
T
A
G
I
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJI5
515
59098
Y260
G
T
E
G
R
G
G
Y
F
D
E
Y
G
I
I
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
Y235
G
T
E
G
R
G
G
Y
F
D
S
I
G
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.9
99
87.8
N.A.
93.7
93.7
N.A.
90.2
N.A.
77.2
75.3
74.3
61.2
63.7
58.8
N.A.
Protein Similarity:
100
69.1
99.6
91.5
N.A.
97
96.6
N.A.
96.1
N.A.
89.7
85.8
82.6
74
76.8
74.9
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
86.6
86.6
93.3
93.3
73.3
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
N.A.
100
100
100
100
100
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.2
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.5
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
93.3
86.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
100
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
94
14
0
0
0
0
% D
% Glu:
0
0
60
0
0
0
0
0
0
0
67
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
94
0
0
74
0
0
0
% F
% Gly:
94
0
7
94
0
87
94
0
0
0
7
0
94
0
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
7
0
0
7
0
94
100
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
34
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
94
0
0
0
0
7
0
0
0
7
0
% R
% Ser:
0
0
0
7
0
0
7
0
0
0
7
0
0
0
0
% S
% Thr:
0
94
0
0
0
0
0
0
0
0
7
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
94
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _