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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: G6PD All Species: 50
Human Site: Y401 Identified Species: 78.57
UniProt: P11413 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11413 NP_000393.4 515 59257 Y401 V Q P N E A V Y T K M M T K K
Chimpanzee Pan troglodytes XP_001146640 398 44780 I286 G Y F D E F G I I R D V M Q N
Rhesus Macaque Macaca mulatta XP_001095273 515 59249 Y401 V Q P N E A V Y T K M M T K K
Dog Lupus familis XP_538209 545 62703 Y431 V Q P N E A V Y T K M M T K K
Cat Felis silvestris
Mouse Mus musculus Q00612 515 59244 Y401 V Q P N E A V Y T K M M T K K
Rat Rattus norvegicus P05370 515 59357 Y401 V Q P N E A V Y T K M M T K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505636 515 59203 Y401 V Q P N E A V Y T K M M T K K
Chicken Gallus gallus
Frog Xenopus laevis NP_001080019 518 59674 Y404 V Q P N E A V Y T K M M T K K
Zebra Danio Brachydanio rerio XP_699168 523 59677 Y409 V Q P N E A I Y A K M M S K K
Tiger Blowfish Takifugu rubipres P54996 530 60451 Y416 V Q P N E A I Y A K M M S K K
Fruit Fly Dros. melanogaster P12646 524 60412 Y406 V Q P G E A L Y F K M M T K S
Honey Bee Apis mellifera XP_001121185 518 60246 G365 V P F I L K C G K A L N E R K
Nematode Worm Caenorhab. elegans Q27464 522 60197 Y409 V Q P N E A V Y M K L M T K K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJI5 515 59098 Y402 L Q P S E A M Y M K L T V K Q
Baker's Yeast Sacchar. cerevisiae P11412 505 57503 Y383 V Q P D A A V Y L K F N A K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.9 99 87.8 N.A. 93.7 93.7 N.A. 90.2 N.A. 77.2 75.3 74.3 61.2 63.7 58.8 N.A.
Protein Similarity: 100 69.1 99.6 91.5 N.A. 97 96.6 N.A. 96.1 N.A. 89.7 85.8 82.6 74 76.8 74.9 N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. 100 N.A. 100 80 80 73.3 13.3 86.6 N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 100 100 N.A. 100 N.A. 100 93.3 93.3 80 26.6 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 52.2 46.4 N.A.
Protein Similarity: N.A. N.A. N.A. 68.5 63.8 N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 87 0 0 14 7 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 14 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 0 0 0 0 87 0 0 0 0 0 0 0 7 0 0 % E
% Phe: 0 0 14 0 0 7 0 0 7 0 7 0 0 0 0 % F
% Gly: 7 0 0 7 0 0 7 7 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 14 7 7 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 7 0 0 7 87 0 0 0 87 74 % K
% Leu: 7 0 0 0 7 0 7 0 7 0 20 0 0 0 0 % L
% Met: 0 0 0 0 0 0 7 0 14 0 67 74 7 0 0 % M
% Asn: 0 0 0 67 0 0 0 0 0 0 0 14 0 0 7 % N
% Pro: 0 7 87 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 87 0 0 0 0 0 0 0 0 0 0 0 7 7 % Q
% Arg: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % R
% Ser: 0 0 0 7 0 0 0 0 0 0 0 0 14 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 47 0 0 7 60 0 7 % T
% Val: 87 0 0 0 0 0 60 0 0 0 0 7 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 87 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _