KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
G6PD
All Species:
51.82
Human Site:
Y424
Identified Species:
81.43
UniProt:
P11413
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11413
NP_000393.4
515
59257
Y424
E
S
E
L
D
L
T
Y
G
N
R
Y
K
N
V
Chimpanzee
Pan troglodytes
XP_001146640
398
44780
S309
V
A
M
E
K
P
A
S
T
N
S
D
D
V
R
Rhesus Macaque
Macaca mulatta
XP_001095273
515
59249
Y424
E
S
E
L
D
L
T
Y
G
N
R
Y
K
N
V
Dog
Lupus familis
XP_538209
545
62703
Y454
E
S
E
L
D
L
T
Y
G
N
R
Y
K
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q00612
515
59244
Y424
E
S
E
L
D
L
T
Y
G
N
R
Y
K
N
V
Rat
Rattus norvegicus
P05370
515
59357
Y424
E
S
E
L
D
L
T
Y
G
N
R
Y
K
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505636
515
59203
Y424
E
S
E
L
D
L
T
Y
G
N
R
Y
K
D
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080019
518
59674
Y427
E
S
E
L
D
L
T
Y
G
S
R
Y
K
D
V
Zebra Danio
Brachydanio rerio
XP_699168
523
59677
Y432
E
T
E
L
D
L
T
Y
H
S
R
Y
R
D
V
Tiger Blowfish
Takifugu rubipres
P54996
530
60451
Y439
E
T
E
L
D
L
T
Y
K
S
R
Y
K
D
V
Fruit Fly
Dros. melanogaster
P12646
524
60412
Y429
E
T
E
L
D
L
T
Y
E
H
R
Y
K
D
S
Honey Bee
Apis mellifera
XP_001121185
518
60246
D388
D
V
P
G
D
I
F
D
G
K
A
K
R
N
E
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
Y432
E
T
E
L
D
L
T
Y
N
N
R
F
K
E
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJI5
515
59098
Y425
Q
S
E
L
D
L
S
Y
G
Q
R
Y
Q
G
V
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
Y406
V
T
D
L
N
L
T
Y
A
S
R
Y
Q
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.9
99
87.8
N.A.
93.7
93.7
N.A.
90.2
N.A.
77.2
75.3
74.3
61.2
63.7
58.8
N.A.
Protein Similarity:
100
69.1
99.6
91.5
N.A.
97
96.6
N.A.
96.1
N.A.
89.7
85.8
82.6
74
76.8
74.9
N.A.
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
93.3
N.A.
86.6
66.6
73.3
66.6
20
73.3
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
N.A.
100
93.3
93.3
86.6
40
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.2
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.5
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
66.6
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
7
0
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
0
87
0
0
7
0
0
0
7
7
40
0
% D
% Glu:
74
0
80
7
0
0
0
0
7
0
0
0
0
7
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
7
% F
% Gly:
0
0
0
7
0
0
0
0
60
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
0
7
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
0
7
7
0
7
67
0
0
% K
% Leu:
0
0
0
87
0
87
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
0
7
54
0
0
0
40
0
% N
% Pro:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
7
0
0
14
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
87
0
14
0
7
% R
% Ser:
0
54
0
0
0
0
7
7
0
27
7
0
0
0
7
% S
% Thr:
0
34
0
0
0
0
80
0
7
0
0
0
0
0
0
% T
% Val:
14
7
0
0
0
0
0
0
0
0
0
0
0
7
74
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
87
0
0
0
80
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _