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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VDR All Species: 1.82
Human Site: S199 Identified Species: 4.44
UniProt: P11473 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11473 NP_000367.1 427 48289 S199 T S S D M M D S S S F S N L D
Chimpanzee Pan troglodytes A2T7D9 348 39540 P147 H L F I H H Q P L P T L A P V
Rhesus Macaque Macaca mulatta Q8SQ01 434 49974 S212 D L W S V K V S V Q L R G E D
Dog Lupus familis XP_543714 448 49978 P220 A L L D V M E P T S F S N L D
Cat Felis silvestris
Mouse Mus musculus P48281 422 47833 P194 P S L D M M E P A S F S T M D
Rat Rattus norvegicus P13053 423 47795 P195 T S L D M M E P S G F S N L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O42392 451 51281 P223 A F P E P M E P Q M F S N L D
Frog Xenopus laevis O13124 422 48170 S194 F T S S P D S S E H G F F S A
Zebra Danio Brachydanio rerio Q9PTN2 453 50848 N227 E S V D T K L N F S N L L M M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001123279 490 55735 L274 P G L M P V S L T P K R S E D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 39.8 88.3 N.A. 88.5 89.6 N.A. N.A. 76 73.3 67.9 N.A. N.A. N.A. N.A. 30.2
Protein Similarity: 100 51.9 56.2 91.7 N.A. 93.2 93.4 N.A. N.A. 84.4 85 78.8 N.A. N.A. N.A. N.A. 48.7
P-Site Identity: 100 0 13.3 53.3 N.A. 53.3 73.3 N.A. N.A. 40 13.3 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 0 20 73.3 N.A. 73.3 80 N.A. N.A. 53.3 20 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 0 0 0 0 0 10 0 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 50 0 10 10 0 0 0 0 0 0 0 70 % D
% Glu: 10 0 0 10 0 0 40 0 10 0 0 0 0 20 0 % E
% Phe: 10 10 10 0 0 0 0 0 10 0 50 10 10 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 10 10 0 10 0 0 % G
% His: 10 0 0 0 10 10 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 20 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 30 40 0 0 0 10 10 10 0 10 20 10 40 0 % L
% Met: 0 0 0 10 30 50 0 0 0 10 0 0 0 20 10 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 10 0 40 0 0 % N
% Pro: 20 0 10 0 30 0 0 50 0 20 0 0 0 10 0 % P
% Gln: 0 0 0 0 0 0 10 0 10 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % R
% Ser: 0 40 20 20 0 0 20 30 20 40 0 50 10 10 0 % S
% Thr: 20 10 0 0 10 0 0 0 20 0 10 0 10 0 0 % T
% Val: 0 0 10 0 20 10 10 0 10 0 0 0 0 0 10 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _