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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VDR All Species: 8.48
Human Site: S200 Identified Species: 20.74
UniProt: P11473 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11473 NP_000367.1 427 48289 S200 S S D M M D S S S F S N L D L
Chimpanzee Pan troglodytes A2T7D9 348 39540 L148 L F I H H Q P L P T L A P V L
Rhesus Macaque Macaca mulatta Q8SQ01 434 49974 V213 L W S V K V S V Q L R G E D G
Dog Lupus familis XP_543714 448 49978 T221 L L D V M E P T S F S N L D L
Cat Felis silvestris
Mouse Mus musculus P48281 422 47833 A195 S L D M M E P A S F S T M D L
Rat Rattus norvegicus P13053 423 47795 S196 S L D M M E P S G F S N L D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O42392 451 51281 Q224 F P E P M E P Q M F S N L D L
Frog Xenopus laevis O13124 422 48170 E195 T S S P D S S E H G F F S A S
Zebra Danio Brachydanio rerio Q9PTN2 453 50848 F228 S V D T K L N F S N L L M M Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001123279 490 55735 T275 G L M P V S L T P K R S E D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 39.8 88.3 N.A. 88.5 89.6 N.A. N.A. 76 73.3 67.9 N.A. N.A. N.A. N.A. 30.2
Protein Similarity: 100 51.9 56.2 91.7 N.A. 93.2 93.4 N.A. N.A. 84.4 85 78.8 N.A. N.A. N.A. N.A. 48.7
P-Site Identity: 100 6.6 13.3 60 N.A. 60 73.3 N.A. N.A. 46.6 13.3 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 6.6 20 80 N.A. 80 80 N.A. N.A. 60 20 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 50 0 10 10 0 0 0 0 0 0 0 70 0 % D
% Glu: 0 0 10 0 0 40 0 10 0 0 0 0 20 0 0 % E
% Phe: 10 10 0 0 0 0 0 10 0 50 10 10 0 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 10 10 0 10 0 0 20 % G
% His: 0 0 0 10 10 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 20 0 0 0 0 10 0 0 0 0 0 % K
% Leu: 30 40 0 0 0 10 10 10 0 10 20 10 40 0 60 % L
% Met: 0 0 10 30 50 0 0 0 10 0 0 0 20 10 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 10 0 40 0 0 0 % N
% Pro: 0 10 0 30 0 0 50 0 20 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 10 0 10 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % R
% Ser: 40 20 20 0 0 20 30 20 40 0 50 10 10 0 10 % S
% Thr: 10 0 0 10 0 0 0 20 0 10 0 10 0 0 0 % T
% Val: 0 10 0 20 10 10 0 10 0 0 0 0 0 10 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _