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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VDR
All Species:
18.48
Human Site:
S216
Identified Species:
45.19
UniProt:
P11473
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11473
NP_000367.1
427
48289
S216
E
E
D
S
D
D
P
S
V
T
L
E
L
S
Q
Chimpanzee
Pan troglodytes
A2T7D9
348
39540
I164
L
V
T
H
F
A
D
I
N
T
F
M
V
L
Q
Rhesus Macaque
Macaca mulatta
Q8SQ01
434
49974
A229
V
W
N
Y
K
P
P
A
D
N
G
G
K
E
I
Dog
Lupus familis
XP_543714
448
49978
S237
E
E
D
S
D
D
S
S
L
T
L
D
L
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P48281
422
47833
S211
E
E
G
S
D
D
P
S
V
T
L
D
L
S
P
Rat
Rattus norvegicus
P13053
423
47795
S212
G
E
D
S
D
D
P
S
V
T
L
D
L
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O42392
451
51281
S240
E
E
S
D
E
S
P
S
M
N
I
E
L
P
H
Frog
Xenopus laevis
O13124
422
48170
S211
F
G
Q
F
E
Y
S
S
M
G
G
K
S
G
E
Zebra Danio
Brachydanio rerio
Q9PTN2
453
50848
S244
D
S
G
S
P
D
S
S
E
E
D
Q
Q
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001123279
490
55735
D291
G
E
E
L
D
D
Q
D
N
D
A
L
H
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
35.1
39.8
88.3
N.A.
88.5
89.6
N.A.
N.A.
76
73.3
67.9
N.A.
N.A.
N.A.
N.A.
30.2
Protein Similarity:
100
51.9
56.2
91.7
N.A.
93.2
93.4
N.A.
N.A.
84.4
85
78.8
N.A.
N.A.
N.A.
N.A.
48.7
P-Site Identity:
100
13.3
6.6
80
N.A.
80
80
N.A.
N.A.
40
6.6
26.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
20
20
93.3
N.A.
86.6
86.6
N.A.
N.A.
60
33.3
46.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
30
10
50
60
10
10
10
10
10
30
0
0
0
% D
% Glu:
40
60
10
0
20
0
0
0
10
10
0
20
0
10
10
% E
% Phe:
10
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
20
10
20
0
0
0
0
0
0
10
20
10
0
10
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
10
10
0
0
% K
% Leu:
10
0
0
10
0
0
0
0
10
0
40
10
50
10
0
% L
% Met:
0
0
0
0
0
0
0
0
20
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
20
20
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
10
50
0
0
0
0
0
0
10
20
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
0
10
10
0
30
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
20
% R
% Ser:
0
10
10
50
0
10
30
70
0
0
0
0
10
50
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
50
0
0
0
0
0
% T
% Val:
10
10
0
0
0
0
0
0
30
0
0
0
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _