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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PC
All Species:
24.24
Human Site:
S523
Identified Species:
48.48
UniProt:
P11498
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11498
NP_000911.2
1178
129634
S523
I
P
V
K
A
S
P
S
P
T
D
P
V
V
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001107749
1178
129775
S523
I
P
V
K
A
S
P
S
P
T
D
P
I
V
P
Dog
Lupus familis
XP_540825
1178
129571
S523
I
P
V
K
A
S
P
S
P
T
D
P
V
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q05920
1178
129666
S523
I
P
V
N
V
S
P
S
P
V
D
P
A
V
P
Rat
Rattus norvegicus
P52873
1178
129758
S523
I
P
V
K
V
S
P
S
P
V
D
P
I
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989677
1178
127225
A523
L
P
V
K
A
K
A
A
V
V
E
P
V
P
P
Frog
Xenopus laevis
NP_001083226
1177
130075
S523
I
P
V
K
A
S
P
S
S
V
D
P
V
I
P
Zebra Danio
Brachydanio rerio
NP_571625
1180
129866
S525
I
P
V
K
A
K
P
S
P
V
D
P
V
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610527
1181
130845
A525
L
A
T
T
L
K
P
A
L
V
S
P
H
V
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17732
1175
129267
A518
L
A
T
D
L
K
P
A
V
V
S
P
P
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42523
734
80433
G201
K
P
T
H
G
G
G
G
K
G
M
R
I
V
Q
Baker's Yeast
Sacchar. cerevisiae
P32327
1180
130148
L508
G
Q
I
G
L
P
K
L
K
S
N
P
S
V
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
97.7
N.A.
96.6
96.3
N.A.
N.A.
77.9
84.2
82.8
N.A.
67.6
N.A.
64.2
N.A.
Protein Similarity:
100
N.A.
99.6
99
N.A.
98.5
98.4
N.A.
N.A.
87.6
92.1
90.4
N.A.
81.5
N.A.
79.2
N.A.
P-Site Identity:
100
N.A.
93.3
100
N.A.
73.3
80
N.A.
N.A.
46.6
80
80
N.A.
26.6
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
73.3
86.6
N.A.
N.A.
66.6
86.6
86.6
N.A.
40
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
53.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
70.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
50
0
9
25
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
0
0
0
59
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
9
9
9
9
0
9
0
0
0
0
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
59
0
9
0
0
0
0
0
0
0
0
0
25
25
0
% I
% Lys:
9
0
0
59
0
34
9
0
17
0
0
0
0
0
0
% K
% Leu:
25
0
0
0
25
0
0
9
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
75
0
0
0
9
75
0
50
0
0
92
9
9
92
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
0
0
0
0
0
50
0
59
9
9
17
0
9
0
0
% S
% Thr:
0
0
25
9
0
0
0
0
0
25
0
0
0
0
0
% T
% Val:
0
0
67
0
17
0
0
0
17
59
0
0
42
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _