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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PC All Species: 28.18
Human Site: T1167 Identified Species: 56.36
UniProt: P11498 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11498 NP_000911.2 1178 129634 T1167 V H V T K D M T L E G D D L I
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001107749 1178 129775 T1167 V H V T K D M T L E G D D L I
Dog Lupus familis XP_540825 1178 129571 T1167 V H V T T D M T L E G D D L I
Cat Felis silvestris
Mouse Mus musculus Q05920 1178 129666 T1167 V H V T K D M T L E G D D L I
Rat Rattus norvegicus P52873 1178 129758 T1167 V H V T K D M T L E G D D L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989677 1178 127225 S1167 L H V R P G M S L E G D D L I
Frog Xenopus laevis NP_001083226 1177 130075 H1166 V H V K L D M H L E G E D L L
Zebra Danio Brachydanio rerio NP_571625 1180 129866 S1168 V H V N A D S S L E G E D L I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610527 1181 130845 K1170 L E I A N G T K L E G E D L I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17732 1175 129267 K1163 I H A P Q G T K C S A G D L V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42523 734 80433 S727 G Q Q V S D G S A L F R I K G
Baker's Yeast Sacchar. cerevisiae P32327 1180 130148 S1159 V F I K D G E S V D A S D L L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.2 97.7 N.A. 96.6 96.3 N.A. N.A. 77.9 84.2 82.8 N.A. 67.6 N.A. 64.2 N.A.
Protein Similarity: 100 N.A. 99.6 99 N.A. 98.5 98.4 N.A. N.A. 87.6 92.1 90.4 N.A. 81.5 N.A. 79.2 N.A.
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 100 N.A. N.A. 66.6 66.6 66.6 N.A. 40 N.A. 20 N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 100 N.A. N.A. 80 80 80 N.A. 60 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28 53.7 N.A.
Protein Similarity: N.A. N.A. N.A. 40.5 70.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 9 0 0 0 9 0 17 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 67 0 0 0 9 0 50 92 0 0 % D
% Glu: 0 9 0 0 0 0 9 0 0 75 0 25 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 9 0 0 0 0 34 9 0 0 0 75 9 0 0 9 % G
% His: 0 75 0 0 0 0 0 9 0 0 0 0 0 0 0 % H
% Ile: 9 0 17 0 0 0 0 0 0 0 0 0 9 0 67 % I
% Lys: 0 0 0 17 34 0 0 17 0 0 0 0 0 9 0 % K
% Leu: 17 0 0 0 9 0 0 0 75 9 0 0 0 92 17 % L
% Met: 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 9 0 9 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 0 0 0 0 9 0 9 34 0 9 0 9 0 0 0 % S
% Thr: 0 0 0 42 9 0 17 42 0 0 0 0 0 0 0 % T
% Val: 67 0 67 9 0 0 0 0 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _