Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PC All Species: 18.18
Human Site: T19 Identified Species: 36.36
UniProt: P11498 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11498 NP_000911.2 1178 129634 T19 R L L G I R R T S T A P A A S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001107749 1178 129775 T19 R L L G I R R T S T A P A A S
Dog Lupus familis XP_540825 1178 129571 S19 R L L G I H R S S T A P A A S
Cat Felis silvestris
Mouse Mus musculus Q05920 1178 129666 S19 R L L G V R R S S S A P V A S
Rat Rattus norvegicus P52873 1178 129758 S19 R L L G V R R S S T A P V A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_989677 1178 127225 L19 A L L G A W R L P L L R P P P
Frog Xenopus laevis NP_001083226 1177 130075 I19 T F L G V K R I S V L N A A F
Zebra Danio Brachydanio rerio NP_571625 1180 129866 G21 I L L I R R A G L F C R S A H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610527 1181 130845 R21 R K T Q P R V R L N A I F K N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17732 1175 129267 Y22 R Q T H Y R N Y A N G V I K P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42523 734 80433
Baker's Yeast Sacchar. cerevisiae P32327 1180 130148 E19 D N F S L L G E K N K I L V A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.2 97.7 N.A. 96.6 96.3 N.A. N.A. 77.9 84.2 82.8 N.A. 67.6 N.A. 64.2 N.A.
Protein Similarity: 100 N.A. 99.6 99 N.A. 98.5 98.4 N.A. N.A. 87.6 92.1 90.4 N.A. 81.5 N.A. 79.2 N.A.
P-Site Identity: 100 N.A. 100 86.6 N.A. 73.3 80 N.A. N.A. 26.6 40 26.6 N.A. 20 N.A. 13.3 N.A.
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. N.A. 26.6 53.3 33.3 N.A. 26.6 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 28 53.7 N.A.
Protein Similarity: N.A. N.A. N.A. 40.5 70.8 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 9 0 9 0 50 0 34 59 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % E
% Phe: 0 9 9 0 0 0 0 0 0 9 0 0 9 0 9 % F
% Gly: 0 0 0 59 0 0 9 9 0 0 9 0 0 0 0 % G
% His: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 9 % H
% Ile: 9 0 0 9 25 0 0 9 0 0 0 17 9 0 0 % I
% Lys: 0 9 0 0 0 9 0 0 9 0 9 0 0 17 0 % K
% Leu: 0 59 67 0 9 9 0 9 17 9 17 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 0 9 0 0 25 0 9 0 0 9 % N
% Pro: 0 0 0 0 9 0 0 0 9 0 0 42 9 9 17 % P
% Gln: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 59 0 0 0 9 59 59 9 0 0 0 17 0 0 0 % R
% Ser: 0 0 0 9 0 0 0 25 50 9 0 0 9 0 42 % S
% Thr: 9 0 17 0 0 0 0 17 0 34 0 0 0 0 0 % T
% Val: 0 0 0 0 25 0 9 0 0 9 0 9 17 9 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _