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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PC
All Species:
27.88
Human Site:
Y593
Identified Species:
55.76
UniProt:
P11498
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11498
NP_000911.2
1178
129634
Y593
D
L
K
K
I
A
P
Y
V
A
H
N
F
S
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001107749
1178
129775
Y593
D
L
K
K
I
A
P
Y
V
A
H
N
F
S
K
Dog
Lupus familis
XP_540825
1178
129571
Y593
D
L
K
K
I
A
P
Y
V
A
H
N
F
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q05920
1178
129666
Y593
D
L
K
K
I
A
P
Y
V
A
H
N
F
N
K
Rat
Rattus norvegicus
P52873
1178
129758
Y593
D
L
K
K
I
A
P
Y
V
A
H
N
F
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989677
1178
127225
F593
D
L
A
R
I
A
P
F
V
A
H
S
L
S
P
Frog
Xenopus laevis
NP_001083226
1177
130075
F593
D
L
K
K
I
A
P
F
V
S
H
N
F
N
N
Zebra Danio
Brachydanio rerio
NP_571625
1180
129866
Y595
D
L
K
K
I
A
P
Y
V
S
H
N
F
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610527
1181
130845
Y596
D
L
L
K
I
S
P
Y
V
T
H
K
F
N
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17732
1175
129267
F589
D
M
A
A
I
S
P
F
V
A
Q
S
F
N
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42523
734
80433
R243
E
K
Y
I
T
R
P
R
H
I
E
V
Q
I
F
Baker's Yeast
Sacchar. cerevisiae
P32327
1180
130148
T588
D
L
A
T
I
A
P
T
T
A
H
A
L
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
97.7
N.A.
96.6
96.3
N.A.
N.A.
77.9
84.2
82.8
N.A.
67.6
N.A.
64.2
N.A.
Protein Similarity:
100
N.A.
99.6
99
N.A.
98.5
98.4
N.A.
N.A.
87.6
92.1
90.4
N.A.
81.5
N.A.
79.2
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
N.A.
60
73.3
86.6
N.A.
60
N.A.
40
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
N.A.
80
93.3
93.3
N.A.
73.3
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
53.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.5
70.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
9
0
75
0
0
0
67
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
92
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
25
0
0
0
0
75
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% G
% His:
0
0
0
0
0
0
0
0
9
0
84
0
0
0
0
% H
% Ile:
0
0
0
9
92
0
0
0
0
9
0
0
0
9
0
% I
% Lys:
0
9
59
67
0
0
0
0
0
0
0
9
0
0
34
% K
% Leu:
0
84
9
0
0
0
0
0
0
0
0
0
17
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
59
0
42
34
% N
% Pro:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% Q
% Arg:
0
0
0
9
0
9
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
17
0
0
0
17
0
17
0
42
0
% S
% Thr:
0
0
0
9
9
0
0
9
9
9
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
84
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
59
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _