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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
24.55
Human Site:
S114
Identified Species:
41.54
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
S114
M
K
H
N
H
Y
S
S
R
F
G
S
K
L
G
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
S114
M
K
H
N
H
Y
S
S
R
F
G
S
K
L
G
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
W88
Y
G
E
F
M
R
V
W
I
S
G
E
E
T
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
S114
M
K
H
S
H
Y
I
S
R
F
G
S
K
R
G
Rat
Rattus norvegicus
P22443
508
58393
S114
M
K
H
S
N
Y
I
S
R
F
G
S
K
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
S113
M
K
H
W
N
Y
V
S
R
F
G
S
K
L
G
Frog
Xenopus laevis
NP_001079122
500
57333
S112
M
K
H
S
H
Y
V
S
R
F
G
S
K
L
G
Zebra Danio
Brachydanio rerio
O42145
509
57336
S134
L
R
K
S
L
Y
T
S
R
F
G
S
K
L
G
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
A116
L
R
S
A
H
Y
T
A
R
F
G
S
R
A
G
Fruit Fly
Dros. melanogaster
Q27589
501
57896
M116
W
L
G
D
G
L
L
M
S
T
G
R
K
W
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
N116
P
E
K
D
E
R
T
N
L
F
S
A
Q
G
F
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
I112
E
K
S
E
T
F
N
I
F
P
F
V
T
H
C
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
E112
P
K
G
K
S
F
T
E
I
L
G
D
L
L
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
E117
P
K
G
A
F
Y
R
E
R
F
R
D
L
L
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
80
73.3
N.A.
N.A.
80
86.6
60
46.6
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
13.3
N.A.
N.A.
86.6
86.6
N.A.
N.A.
86.6
93.3
86.6
80
20
N.A.
46.6
20
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
40
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
8
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
15
0
0
0
0
0
0
0
15
0
0
0
% D
% Glu:
8
8
8
8
8
0
0
15
0
0
0
8
8
0
8
% E
% Phe:
0
0
0
8
8
15
0
0
8
72
8
0
0
0
8
% F
% Gly:
0
8
22
0
8
0
0
0
0
0
79
0
0
8
65
% G
% His:
0
0
43
0
36
0
0
0
0
0
0
0
0
8
8
% H
% Ile:
0
0
0
0
0
0
15
8
15
0
0
0
0
0
0
% I
% Lys:
0
65
15
8
0
0
0
0
0
0
0
0
58
0
0
% K
% Leu:
15
8
0
0
8
8
8
0
8
8
0
0
15
50
8
% L
% Met:
43
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
15
15
0
8
8
0
0
0
0
0
0
0
% N
% Pro:
22
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
15
0
0
0
15
8
0
65
0
8
8
8
15
0
% R
% Ser:
0
0
15
29
8
0
15
50
8
8
8
58
0
0
0
% S
% Thr:
0
0
0
0
8
0
29
0
0
8
0
0
8
8
0
% T
% Val:
0
0
0
0
0
0
22
0
0
0
0
8
0
0
0
% V
% Trp:
8
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% W
% Tyr:
8
0
0
0
0
65
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _