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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
16.97
Human Site:
S247
Identified Species:
28.72
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
S247
L
Y
K
K
Y
E
K
S
V
K
D
L
K
D
A
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
S247
L
Y
K
K
Y
E
K
S
V
K
D
L
K
D
A
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
L208
M
L
F
L
R
I
P
L
D
E
S
A
I
V
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
S247
L
Y
R
K
Y
E
R
S
V
K
D
L
K
D
E
Rat
Rattus norvegicus
P22443
508
58393
S247
L
Y
R
K
Y
E
R
S
V
K
D
L
K
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
A246
L
C
K
K
Y
E
E
A
A
K
D
L
K
G
A
Frog
Xenopus laevis
NP_001079122
500
57333
S245
L
Y
K
K
Y
E
K
S
A
N
D
L
K
E
A
Zebra Danio
Brachydanio rerio
O42145
509
57336
D267
L
H
R
K
H
K
R
D
A
Q
E
L
Q
D
A
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
A249
L
F
D
K
H
R
R
A
A
Q
E
L
Q
D
T
Fruit Fly
Dros. melanogaster
Q27589
501
57896
A239
E
A
K
R
Q
D
K
A
I
K
V
M
H
D
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
R262
V
Q
N
R
I
D
Q
R
E
N
D
R
K
N
G
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
R234
A
V
T
R
K
R
K
R
I
A
F
L
D
L
L
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
A251
A
E
K
K
L
K
E
A
I
K
L
V
H
D
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
K251
L
G
I
G
Y
E
R
K
L
N
N
A
V
R
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
0
N.A.
N.A.
80
80
N.A.
N.A.
66.6
80
33.3
26.6
26.6
N.A.
13.3
13.3
P-Site Similarity:
100
100
13.3
N.A.
N.A.
93.3
93.3
N.A.
N.A.
80
86.6
86.6
73.3
60
N.A.
46.6
26.6
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
0
0
0
0
29
29
8
0
15
0
0
36
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
15
0
8
8
0
50
0
8
58
0
% D
% Glu:
8
8
0
0
0
50
15
0
8
8
15
0
0
8
15
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
8
% F
% Gly:
0
8
0
8
0
0
0
0
0
0
0
0
0
8
8
% G
% His:
0
8
0
0
15
0
0
0
0
0
0
0
15
0
0
% H
% Ile:
0
0
8
0
8
8
0
0
22
0
0
0
8
0
8
% I
% Lys:
0
0
43
65
8
15
36
8
0
50
0
0
50
0
0
% K
% Leu:
65
8
0
8
8
0
0
8
8
0
8
65
0
8
8
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
22
8
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
0
8
0
0
15
0
0
15
0
0
% Q
% Arg:
0
0
22
22
8
15
36
15
0
0
0
8
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
36
0
0
8
0
0
0
8
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
8
8
0
0
0
0
0
0
29
0
8
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
36
0
0
50
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _