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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
21.82
Human Site:
S45
Identified Species:
36.92
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
S45
V
W
N
Y
E
G
T
S
S
I
P
G
P
G
Y
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
S45
V
W
N
Y
E
G
T
S
S
I
P
G
P
G
Y
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
E19
N
I
T
S
M
V
P
E
A
M
P
A
A
T
M
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
S45
I
W
N
C
E
S
S
S
S
I
P
G
P
G
Y
Rat
Rattus norvegicus
P22443
508
58393
S45
I
R
N
C
E
S
S
S
S
I
P
G
P
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
S44
I
W
N
H
E
E
T
S
S
I
P
G
P
G
Y
Frog
Xenopus laevis
NP_001079122
500
57333
S43
L
W
N
Q
E
E
T
S
L
I
P
G
P
A
Y
Zebra Danio
Brachydanio rerio
O42145
509
57336
S65
R
H
H
R
P
H
K
S
H
I
P
G
P
S
F
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
Q47
T
W
N
R
P
Q
R
Q
H
V
P
G
P
L
F
Fruit Fly
Dros. melanogaster
Q27589
501
57896
R47
L
G
N
L
L
M
Y
R
G
L
D
P
E
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
L47
V
G
S
F
P
K
T
L
K
S
E
Y
P
Q
Y
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
P43
I
S
K
F
D
G
P
P
A
V
P
I
F
G
N
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
P43
T
H
G
P
P
S
Y
P
I
I
G
C
L
I
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
V48
G
G
P
V
M
W
P
V
L
G
I
I
P
M
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
73.3
66.6
N.A.
N.A.
80
66.6
33.3
33.3
6.6
N.A.
26.6
20
P-Site Similarity:
100
100
20
N.A.
N.A.
86.6
80
N.A.
N.A.
93.3
73.3
46.6
46.6
20
N.A.
40
53.3
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
15
0
0
8
8
8
0
% A
% Cys:
0
0
0
15
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
43
15
0
8
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
15
0
0
0
0
0
0
0
0
8
0
15
% F
% Gly:
8
22
8
0
0
22
0
0
8
8
8
58
0
43
0
% G
% His:
0
15
8
8
0
8
0
0
15
0
0
0
0
0
0
% H
% Ile:
29
8
0
0
0
0
0
0
8
58
8
15
0
8
8
% I
% Lys:
0
0
8
0
0
8
8
0
8
0
0
0
0
0
0
% K
% Leu:
15
0
0
8
8
0
0
8
15
8
0
0
8
8
8
% L
% Met:
0
0
0
0
15
8
0
0
0
8
0
0
0
8
8
% M
% Asn:
8
0
58
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
0
8
8
29
0
22
15
0
0
72
8
72
0
0
% P
% Gln:
0
0
0
8
0
8
0
8
0
0
0
0
0
15
0
% Q
% Arg:
8
8
0
15
0
0
8
8
0
0
0
0
0
0
0
% R
% Ser:
0
8
8
8
0
22
15
50
36
8
0
0
0
8
8
% S
% Thr:
15
0
8
0
0
0
36
0
0
0
0
0
0
8
0
% T
% Val:
22
0
0
8
0
8
0
8
0
15
0
0
0
0
0
% V
% Trp:
0
43
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
0
15
0
0
0
0
8
0
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _