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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
5.76
Human Site:
T162
Identified Species:
9.74
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
T162
P
G
L
V
R
M
V
T
V
C
A
E
S
L
K
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
T162
P
G
L
V
R
M
V
T
V
C
A
E
S
L
K
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
G126
K
L
G
L
Q
C
I
G
M
H
E
K
G
I
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
E162
P
G
L
V
R
M
V
E
V
C
V
E
S
I
K
Rat
Rattus norvegicus
P22443
508
58393
E162
P
G
L
I
R
M
V
E
V
C
V
E
S
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
A161
P
G
L
V
R
M
I
A
I
C
V
E
S
T
I
Frog
Xenopus laevis
NP_001079122
500
57333
E160
P
G
L
M
Q
T
T
E
N
C
I
R
S
T
N
Zebra Danio
Brachydanio rerio
O42145
509
57336
E182
P
G
L
Q
R
T
M
E
I
C
T
T
S
T
N
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
G164
P
G
L
Q
R
T
V
G
V
C
V
T
S
T
A
Fruit Fly
Dros. melanogaster
Q27589
501
57896
L156
S
A
V
M
V
E
Q
L
Q
S
R
A
D
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
T163
L
R
H
I
E
E
Q
T
S
E
G
Q
Q
I
D
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
R152
R
A
V
D
S
M
S
R
L
V
V
R
R
M
R
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
E156
F
V
V
M
T
L
Q
E
E
V
E
N
R
L
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
L167
R
D
L
V
D
Q
K
L
V
P
L
M
E
N
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
0
N.A.
N.A.
80
73.3
N.A.
N.A.
60
33.3
40
53.3
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
40
N.A.
N.A.
86.6
86.6
N.A.
N.A.
73.3
46.6
53.3
53.3
20
N.A.
26.6
33.3
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
0
8
0
0
15
8
0
0
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
58
0
0
0
0
0
% C
% Asp:
0
8
0
8
8
0
0
0
0
0
0
0
8
0
8
% D
% Glu:
0
0
0
0
8
15
0
36
8
8
15
36
8
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
58
8
0
0
0
0
15
0
0
8
0
8
8
0
% G
% His:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
15
0
0
15
0
15
0
8
0
0
29
22
% I
% Lys:
8
0
0
0
0
0
8
0
0
0
0
8
0
0
36
% K
% Leu:
8
8
65
8
0
8
0
15
8
0
8
0
0
22
8
% L
% Met:
0
0
0
22
0
43
8
0
8
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
15
% N
% Pro:
58
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
15
15
8
22
0
8
0
0
8
8
0
0
% Q
% Arg:
15
8
0
0
50
0
0
8
0
0
8
15
15
0
8
% R
% Ser:
8
0
0
0
8
0
8
0
8
8
0
0
58
0
0
% S
% Thr:
0
0
0
0
8
22
8
22
0
0
8
15
0
29
0
% T
% Val:
0
8
22
36
8
0
36
0
43
15
36
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _