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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
28.18
Human Site:
T179
Identified Species:
47.69
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
T179
L
D
R
L
E
E
V
T
N
E
S
G
Y
V
D
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
T179
L
D
R
L
E
E
V
T
N
E
S
G
Y
V
D
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
T143
N
N
P
D
L
W
K
T
T
R
P
F
F
M
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
T179
L
D
R
L
G
E
V
T
D
T
S
G
Y
V
D
Rat
Rattus norvegicus
P22443
508
58393
T179
L
D
R
L
G
D
V
T
D
N
S
G
Y
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
T178
L
D
K
L
E
E
V
T
T
E
V
G
N
V
N
Frog
Xenopus laevis
NP_001079122
500
57333
T177
L
D
N
L
S
N
V
T
N
E
L
G
N
V
D
Zebra Danio
Brachydanio rerio
O42145
509
57336
T199
L
D
D
L
S
Q
L
T
D
A
Q
G
Q
L
D
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
T181
L
D
C
L
V
D
M
T
D
A
S
G
H
V
D
Fruit Fly
Dros. melanogaster
Q27589
501
57896
C173
I
N
I
F
P
V
I
C
L
T
A
L
D
I
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
M180
Q
F
Y
Q
E
F
T
M
D
T
I
G
R
I
A
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
Y169
L
C
W
S
D
W
I
Y
Y
N
M
G
V
G
K
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
K173
L
E
E
A
V
E
A
K
S
V
L
D
L
Q
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
Q184
S
K
R
V
F
D
L
Q
D
L
L
L
R
F
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
80
73.3
N.A.
N.A.
66.6
66.6
40
53.3
0
N.A.
13.3
13.3
P-Site Similarity:
100
100
26.6
N.A.
N.A.
86.6
86.6
N.A.
N.A.
80
66.6
66.6
80
33.3
N.A.
26.6
26.6
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
15
8
0
0
0
8
% A
% Cys:
0
8
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
58
8
8
8
22
0
0
43
0
0
8
8
0
58
% D
% Glu:
0
8
8
0
29
36
0
0
0
29
0
0
0
0
0
% E
% Phe:
0
8
0
8
8
8
0
0
0
0
0
8
8
8
0
% F
% Gly:
0
0
0
0
15
0
0
0
0
0
0
72
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
8
0
0
0
15
0
0
0
8
0
0
15
8
% I
% Lys:
0
8
8
0
0
0
8
8
0
0
0
0
0
0
15
% K
% Leu:
72
0
0
58
8
0
15
0
8
8
22
15
8
8
0
% L
% Met:
0
0
0
0
0
0
8
8
0
0
8
0
0
8
0
% M
% Asn:
8
15
8
0
0
8
0
0
22
15
0
0
15
0
8
% N
% Pro:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
0
8
0
8
0
8
0
0
8
0
8
8
0
% Q
% Arg:
0
0
36
0
0
0
0
0
0
8
0
0
15
0
0
% R
% Ser:
8
0
0
8
15
0
0
0
8
0
36
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
65
15
22
0
0
0
0
8
% T
% Val:
0
0
0
8
15
8
43
0
0
8
8
0
8
50
0
% V
% Trp:
0
0
8
0
0
15
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
8
8
0
0
0
29
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _