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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
30.91
Human Site:
T292
Identified Species:
52.31
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
T292
A
E
K
R
G
D
L
T
R
E
N
V
N
Q
C
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
T292
A
E
K
R
G
D
L
T
R
E
N
V
N
Q
C
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
V248
Y
K
K
Y
E
K
S
V
K
D
L
K
D
A
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
T292
A
E
R
R
G
D
L
T
K
E
N
V
N
Q
C
Rat
Rattus norvegicus
P22443
508
58393
T292
A
E
R
R
G
D
L
T
K
E
N
V
N
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
T291
A
Q
N
R
G
D
L
T
A
E
N
V
N
Q
C
Frog
Xenopus laevis
NP_001079122
500
57333
T290
A
Q
N
H
G
D
L
T
A
E
N
V
N
Q
C
Zebra Danio
Brachydanio rerio
O42145
509
57336
S311
A
Q
S
H
G
E
L
S
A
E
N
V
R
Q
C
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
S294
A
Q
E
A
G
E
F
S
A
D
N
V
R
Q
C
Fruit Fly
Dros. melanogaster
Q27589
501
57896
L287
M
A
L
L
D
V
L
L
Q
S
T
I
D
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
T313
Y
G
N
R
Q
L
T
T
Q
E
I
V
G
Q
C
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
S276
D
T
T
S
A
A
V
S
W
A
L
L
L
I
G
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
V295
L
A
G
H
G
E
E
V
V
R
D
M
V
I
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
D300
R
E
Y
E
K
E
E
D
T
T
R
G
N
Y
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
86.6
86.6
N.A.
N.A.
80
73.3
53.3
40
6.6
N.A.
40
0
P-Site Similarity:
100
100
33.3
N.A.
N.A.
100
100
N.A.
N.A.
86.6
80
73.3
73.3
26.6
N.A.
46.6
20
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
15
0
8
8
8
0
0
29
8
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
65
% C
% Asp:
8
0
0
0
8
43
0
8
0
15
8
0
15
0
0
% D
% Glu:
0
36
8
8
8
29
15
0
0
58
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
0
8
8
0
65
0
0
0
0
0
0
8
8
8
8
% G
% His:
0
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
8
0
15
8
% I
% Lys:
0
8
22
0
8
8
0
0
22
0
0
8
0
0
0
% K
% Leu:
8
0
8
8
0
8
58
8
0
0
15
8
8
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
22
0
0
0
0
0
0
0
58
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
29
0
0
8
0
0
0
15
0
0
0
0
65
0
% Q
% Arg:
8
0
15
43
0
0
0
0
15
8
8
0
15
0
0
% R
% Ser:
0
0
8
8
0
0
8
22
0
8
0
0
0
0
8
% S
% Thr:
0
8
8
0
0
0
8
50
8
8
8
0
0
0
0
% T
% Val:
0
0
0
0
0
8
8
15
8
0
0
65
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
15
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _