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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
15.15
Human Site:
T493
Identified Species:
25.64
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
T493
N
M
L
E
M
I
F
T
P
R
N
S
D
R
C
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
T493
N
M
L
E
M
I
F
T
P
R
N
S
D
R
C
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
N417
P
N
E
F
T
L
E
N
F
A
K
N
V
R
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
S493
H
L
V
E
I
I
F
S
P
R
N
S
D
K
Y
Rat
Rattus norvegicus
P22443
508
58393
R493
P
I
V
E
I
I
F
R
H
I
F
N
T
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
T492
P
L
L
E
M
V
F
T
Q
E
A
Q
T
R
I
Frog
Xenopus laevis
NP_001079122
500
57333
I491
P
S
L
E
M
I
F
I
P
K
N
T
A
E
F
Zebra Danio
Brachydanio rerio
O42145
509
57336
T493
T
V
E
N
I
P
Q
T
N
N
L
S
Q
Q
P
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
T497
V
C
P
R
H
G
C
T
L
T
S
I
R
Q
T
Fruit Fly
Dros. melanogaster
Q27589
501
57896
S489
S
M
N
I
V
L
R
S
A
N
G
V
H
L
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
Q507
L
V
G
R
A
T
T
Q
P
E
T
V
W
M
H
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
G449
L
I
L
R
P
A
E
G
T
I
L
V
K
L
S
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
A490
V
F
A
P
L
L
T
A
H
M
V
G
G
L
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
N511
T
T
T
L
Y
M
K
N
G
M
N
V
M
L
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
53.3
20
N.A.
N.A.
40
46.6
13.3
6.6
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
100
20
N.A.
N.A.
93.3
46.6
N.A.
N.A.
53.3
60
33.3
20
33.3
N.A.
13.3
13.3
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
8
8
0
8
8
8
8
0
8
0
8
% A
% Cys:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
15
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% D
% Glu:
0
0
15
43
0
0
15
0
0
15
0
0
0
8
0
% E
% Phe:
0
8
0
8
0
0
43
0
8
0
8
0
0
0
15
% F
% Gly:
0
0
8
0
0
8
0
8
8
0
8
8
8
0
8
% G
% His:
8
0
0
0
8
0
0
0
15
0
0
0
8
0
8
% H
% Ile:
0
15
0
8
22
36
0
8
0
15
0
8
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
8
8
0
8
8
8
% K
% Leu:
15
15
36
8
8
22
0
0
8
0
15
0
0
29
0
% L
% Met:
0
22
0
0
29
8
0
0
0
15
0
0
8
8
0
% M
% Asn:
15
8
8
8
0
0
0
15
8
15
36
15
0
0
0
% N
% Pro:
29
0
8
8
8
8
0
0
36
0
0
0
0
8
8
% P
% Gln:
0
0
0
0
0
0
8
8
8
0
0
8
8
15
8
% Q
% Arg:
0
0
0
22
0
0
8
8
0
22
0
0
8
29
0
% R
% Ser:
8
8
0
0
0
0
0
15
0
0
8
29
0
0
8
% S
% Thr:
15
8
8
0
8
8
15
36
8
8
8
8
15
0
8
% T
% Val:
15
15
15
0
8
8
0
0
0
0
8
29
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _