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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
29.39
Human Site:
Y386
Identified Species:
49.74
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
Y386
E
D
D
V
I
D
G
Y
P
V
K
K
G
T
N
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
Y386
E
D
D
V
I
D
G
Y
P
V
K
K
G
T
N
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
F317
T
M
S
V
S
L
F
F
M
L
F
L
I
A
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
Y386
E
D
D
V
I
D
G
Y
P
V
K
K
G
T
N
Rat
Rattus norvegicus
P22443
508
58393
Y386
E
D
D
V
I
D
G
Y
P
V
K
K
G
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
Y385
Q
D
D
V
I
D
G
Y
P
V
K
K
G
T
N
Frog
Xenopus laevis
NP_001079122
500
57333
Y384
E
D
D
I
I
D
G
Y
Y
V
K
K
G
T
N
Zebra Danio
Brachydanio rerio
O42145
509
57336
T392
F
H
P
V
V
D
F
T
M
R
R
A
L
D
D
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
I390
E
D
D
T
I
E
G
I
R
I
R
K
G
T
N
Fruit Fly
Dros. melanogaster
Q27589
501
57896
V389
G
R
W
F
A
E
D
V
E
I
R
G
K
H
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
V407
R
A
T
K
L
G
N
V
E
V
E
V
G
T
M
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
K348
E
D
I
V
V
D
G
K
V
L
P
K
E
A
M
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
T389
D
D
V
L
P
D
G
T
S
V
R
K
G
D
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
T410
D
D
V
L
P
D
G
T
R
V
K
K
G
A
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
N.A.
93.3
86.6
13.3
60
0
N.A.
20
40
P-Site Similarity:
100
100
20
N.A.
N.A.
100
100
N.A.
N.A.
100
93.3
33.3
80
20
N.A.
33.3
53.3
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
40
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
0
0
0
0
0
0
8
0
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
72
50
0
0
72
8
0
0
0
0
0
0
15
8
% D
% Glu:
50
0
0
0
0
15
0
0
15
0
8
0
8
0
0
% E
% Phe:
8
0
0
8
0
0
15
8
0
0
8
0
0
0
0
% F
% Gly:
8
0
0
0
0
8
72
0
0
0
0
8
72
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
8
50
0
0
8
0
15
0
0
8
0
8
% I
% Lys:
0
0
0
8
0
0
0
8
0
0
50
72
8
0
8
% K
% Leu:
0
0
0
15
8
8
0
0
0
15
0
8
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
15
0
0
0
0
0
15
% M
% Asn:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
50
% N
% Pro:
0
0
8
0
15
0
0
0
36
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
8
0
0
0
0
0
0
15
8
29
0
0
0
15
% R
% Ser:
0
0
8
0
8
0
0
0
8
0
0
0
0
0
0
% S
% Thr:
8
0
8
8
0
0
0
22
0
0
0
0
0
58
0
% T
% Val:
0
0
15
58
15
0
0
15
8
65
0
8
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _