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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
20.3
Human Site:
Y441
Identified Species:
34.36
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
Y441
P
R
G
C
A
G
K
Y
I
A
M
V
M
M
K
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
Y441
P
R
G
C
A
G
K
Y
I
A
M
V
M
M
K
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
R365
N
F
I
Y
E
S
M
R
Y
Q
P
V
V
D
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
Y441
P
R
G
C
A
G
K
Y
I
A
M
V
M
M
K
Rat
Rattus norvegicus
P22443
508
58393
Y441
P
R
S
C
A
G
K
Y
I
A
M
V
M
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
F440
P
R
G
C
V
G
K
F
I
A
M
V
M
M
K
Frog
Xenopus laevis
NP_001079122
500
57333
Y439
P
R
A
C
A
G
K
Y
I
A
M
V
M
M
K
Zebra Danio
Brachydanio rerio
O42145
509
57336
V441
L
D
N
F
H
K
N
V
P
S
R
F
F
Q
P
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
T445
R
A
G
A
G
W
L
T
S
S
S
A
P
Q
V
Fruit Fly
Dros. melanogaster
Q27589
501
57896
Y437
D
V
P
Q
I
H
P
Y
A
Y
I
P
F
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
Y455
Q
V
F
Q
K
G
G
Y
I
S
F
G
L
G
P
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
F397
H
P
F
A
F
I
P
F
S
A
G
P
R
N
C
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
P438
Q
T
L
K
S
V
S
P
Y
T
F
P
V
F
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
V459
S
E
D
Q
F
K
Y
V
V
F
N
G
G
P
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
93.3
N.A.
N.A.
86.6
93.3
0
6.6
6.6
N.A.
20
6.6
P-Site Similarity:
100
100
13.3
N.A.
N.A.
100
93.3
N.A.
N.A.
93.3
93.3
6.6
13.3
13.3
N.A.
33.3
13.3
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
15
36
0
0
0
8
50
0
8
0
0
8
% A
% Cys:
0
0
0
43
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
8
8
8
0
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
15
8
15
0
0
15
0
8
15
8
15
8
0
% F
% Gly:
0
0
36
0
8
50
8
0
0
0
8
15
8
8
0
% G
% His:
8
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
8
0
0
50
0
8
0
0
0
0
% I
% Lys:
0
0
0
8
8
15
43
0
0
0
0
0
0
0
43
% K
% Leu:
8
0
8
0
0
0
8
0
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
0
43
0
43
43
0
% M
% Asn:
8
0
8
0
0
0
8
0
0
0
8
0
0
8
0
% N
% Pro:
43
8
8
0
0
0
15
8
8
0
8
22
8
8
15
% P
% Gln:
15
0
0
22
0
0
0
0
0
8
0
0
0
15
8
% Q
% Arg:
8
43
0
0
0
0
0
8
0
0
8
0
8
0
8
% R
% Ser:
8
0
8
0
8
8
8
0
15
22
8
0
0
8
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
15
0
0
8
8
0
15
8
0
0
50
15
0
8
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
50
15
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _