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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP19A1
All Species:
28.18
Human Site:
Y77
Identified Species:
47.69
UniProt:
P11511
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11511
NP_000094.2
503
57883
Y77
I
G
S
A
C
N
Y
Y
N
R
V
Y
G
E
F
Chimpanzee
Pan troglodytes
XP_001169384
503
57882
Y77
I
G
S
A
C
N
Y
Y
N
R
V
Y
G
E
F
Rhesus Macaque
Macaca mulatta
XP_001082665
426
48911
G51
T
S
S
I
P
G
P
G
Y
C
M
G
I
G
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P28649
503
57997
Y77
I
G
S
A
C
N
Y
Y
N
K
M
Y
G
E
F
Rat
Rattus norvegicus
P22443
508
58393
Y77
I
G
S
A
C
N
Y
Y
N
K
M
Y
G
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P19098
507
58128
Y76
V
G
N
A
C
N
Y
Y
N
K
T
Y
G
E
F
Frog
Xenopus laevis
NP_001079122
500
57333
Y75
I
G
K
A
A
N
Y
Y
N
N
M
Y
G
E
F
Zebra Danio
Brachydanio rerio
O42145
509
57336
Y97
I
G
T
A
S
N
Y
Y
N
S
K
Y
G
D
I
Tiger Blowfish
Takifugu rubipres
NP_001166967
531
59842
Y79
I
G
T
A
C
N
F
Y
N
N
K
Y
G
S
L
Fruit Fly
Dros. melanogaster
Q27589
501
57896
V79
W
I
L
H
Q
L
A
V
F
S
T
D
P
R
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09653
519
59999
I79
E
G
T
I
K
T
L
I
V
S
D
I
D
I
V
Sea Urchin
Strong. purpuratus
XP_783176
459
52654
P75
H
R
R
K
L
L
T
P
T
F
H
F
S
I
L
Poplar Tree
Populus trichocarpa
XP_002318721
509
58015
V75
V
S
P
T
Q
T
I
V
V
K
R
L
G
A
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_173862
522
61037
R80
S
G
G
T
F
H
Y
R
G
I
W
F
G
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
82.6
N.A.
N.A.
79.3
75.9
N.A.
N.A.
71
69.7
49.9
49.9
26.2
N.A.
20.2
25
Protein Similarity:
100
100
84.4
N.A.
N.A.
90.8
88.7
N.A.
N.A.
85.8
83.3
71.9
67.8
47.3
N.A.
38.5
42.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
86.6
86.6
N.A.
N.A.
73.3
73.3
60
60
0
N.A.
6.6
0
P-Site Similarity:
100
100
13.3
N.A.
N.A.
100
100
N.A.
N.A.
93.3
80
73.3
73.3
0
N.A.
13.3
6.6
Percent
Protein Identity:
24.5
N.A.
N.A.
25.6
N.A.
N.A.
Protein Similarity:
44.9
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
58
8
0
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
43
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
8
8
8
8
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
43
0
% E
% Phe:
0
0
0
0
8
0
8
0
8
8
0
15
0
0
43
% F
% Gly:
0
72
8
0
0
8
0
8
8
0
0
8
72
15
0
% G
% His:
8
0
0
8
0
8
0
0
0
0
8
0
0
0
0
% H
% Ile:
50
8
0
15
0
0
8
8
0
8
0
8
8
15
8
% I
% Lys:
0
0
8
8
8
0
0
0
0
29
15
0
0
0
0
% K
% Leu:
0
0
8
0
8
15
8
0
0
0
0
8
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
29
0
0
0
0
% M
% Asn:
0
0
8
0
0
58
0
0
58
15
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
0
8
8
0
0
0
0
8
0
8
% P
% Gln:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
0
0
0
0
8
0
15
8
0
0
8
8
% R
% Ser:
8
15
36
0
8
0
0
0
0
22
0
0
8
8
0
% S
% Thr:
8
0
22
15
0
15
8
0
8
0
15
0
0
0
0
% T
% Val:
15
0
0
0
0
0
0
15
15
0
15
0
0
0
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
58
58
8
0
0
58
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _