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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPX All Species: 13.33
Human Site: S64 Identified Species: 26.67
UniProt: P11678 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11678 NP_000493.1 715 81040 S64 S I K Q R L R S G S A S P M D
Chimpanzee Pan troglodytes XP_523809 715 81024 S64 S I K Q R L R S G S A S P M D
Rhesus Macaque Macaca mulatta XP_001106246 715 81154 S64 S I K Q R L R S G S A S P M D
Dog Lupus familis XP_548229 671 75650 A57 E A K L L V D A A Y N Q T Q R
Cat Felis silvestris
Mouse Mus musculus P49290 716 81408 S65 S I M Q R L R S G S A S P M D
Rat Rattus norvegicus P14650 914 101442 R65 M K R N L K K R G V L S P A Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506188 452 51695
Chicken Gallus gallus XP_415716 753 85100 N89 R I K K N L E N D A L N P I E
Frog Xenopus laevis NP_001081848 713 80479 R64 M L K D R L R R R T V S A S D
Zebra Danio Brachydanio rerio NP_997944 762 85101 K58 E S L A R V R K D V I K P S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 K686 L F S N R S D K A P P N Y G E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318 G340 K V N C E V M G N P K P T I N
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.7 79.5 N.A. 88.9 35.6 N.A. 49.9 58.4 56.7 46.7 N.A. 22.9 N.A. 25.7 N.A.
Protein Similarity: 100 99.7 98 86.2 N.A. 94.1 49.8 N.A. 57.6 71.7 71.3 61.9 N.A. 33.9 N.A. 37.2 N.A.
P-Site Identity: 100 100 100 6.6 N.A. 93.3 20 N.A. 0 26.6 40 26.6 N.A. 6.6 N.A. 0 N.A.
P-Site Similarity: 100 100 100 20 N.A. 93.3 33.3 N.A. 0 66.6 53.3 33.3 N.A. 20 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 9 17 9 34 0 9 9 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 17 0 17 0 0 0 0 0 50 % D
% Glu: 17 0 0 0 9 0 9 0 0 0 0 0 0 0 17 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 42 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 42 0 0 0 0 0 0 0 0 9 0 0 17 0 % I
% Lys: 9 9 50 9 0 9 9 17 0 0 9 9 0 0 0 % K
% Leu: 9 9 9 9 17 50 0 0 0 0 17 0 0 0 0 % L
% Met: 17 0 9 0 0 0 9 0 0 0 0 0 0 34 0 % M
% Asn: 0 0 9 17 9 0 0 9 9 0 9 17 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 17 9 9 59 0 0 % P
% Gln: 0 0 0 34 0 0 0 0 0 0 0 9 0 9 9 % Q
% Arg: 9 0 9 0 59 0 50 17 9 0 0 0 0 0 9 % R
% Ser: 34 9 9 0 0 9 0 34 0 34 0 50 0 17 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 9 0 0 17 0 0 % T
% Val: 0 9 0 0 0 25 0 0 0 17 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _