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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPX All Species: 24.55
Human Site: T256 Identified Species: 49.09
UniProt: P11678 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11678 NP_000493.1 715 81040 T256 A G V D C E R T C A Q L P P C
Chimpanzee Pan troglodytes XP_523809 715 81024 T256 A G V D C E R T C A Q L P P C
Rhesus Macaque Macaca mulatta XP_001106246 715 81154 T256 E G V D C E K T C A Q L P P C
Dog Lupus familis XP_548229 671 75650 R242 R D C I P F F R S A P A C P Q
Cat Felis silvestris
Mouse Mus musculus P49290 716 81408 T257 M G V D C E K T C A Q L P P C
Rat Rattus norvegicus P14650 914 101442 T256 G G V D C Q L T C E N Q N P C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506188 452 51695 F88 S G R S L L P F D N L S D D P
Chicken Gallus gallus XP_415716 753 85100 S283 G R V D C H T S C A K L P P C
Frog Xenopus laevis NP_001081848 713 80479 N256 E G I D C D T N C A K E P P C
Zebra Danio Brachydanio rerio NP_997944 762 85101 S255 N G I D C E N S C E R S E P C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 C886 G I D C K K S C E M A P P C Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318 T743 T G A F C N R T C E N L D P C
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 96.7 79.5 N.A. 88.9 35.6 N.A. 49.9 58.4 56.7 46.7 N.A. 22.9 N.A. 25.7 N.A.
Protein Similarity: 100 99.7 98 86.2 N.A. 94.1 49.8 N.A. 57.6 71.7 71.3 61.9 N.A. 33.9 N.A. 37.2 N.A.
P-Site Identity: 100 100 86.6 13.3 N.A. 86.6 53.3 N.A. 6.6 60 53.3 46.6 N.A. 6.6 N.A. 53.3 N.A.
P-Site Similarity: 100 100 93.3 13.3 N.A. 93.3 60 N.A. 13.3 73.3 73.3 66.6 N.A. 13.3 N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 9 0 0 0 0 0 0 59 9 9 0 0 0 % A
% Cys: 0 0 9 9 75 0 0 9 75 0 0 0 9 9 75 % C
% Asp: 0 9 9 67 0 9 0 0 9 0 0 0 17 9 0 % D
% Glu: 17 0 0 0 0 42 0 0 9 25 0 9 9 0 0 % E
% Phe: 0 0 0 9 0 9 9 9 0 0 0 0 0 0 0 % F
% Gly: 25 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 17 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 9 17 0 0 0 17 0 0 0 0 % K
% Leu: 0 0 0 0 9 9 9 0 0 0 9 50 0 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 9 0 0 0 0 9 9 9 0 9 17 0 9 0 0 % N
% Pro: 0 0 0 0 9 0 9 0 0 0 9 9 59 84 9 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 34 9 0 0 9 % Q
% Arg: 9 9 9 0 0 0 25 9 0 0 9 0 0 0 0 % R
% Ser: 9 0 0 9 0 0 9 17 9 0 0 17 0 0 0 % S
% Thr: 9 0 0 0 0 0 17 50 0 0 0 0 0 0 0 % T
% Val: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _