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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADH5
All Species:
43.94
Human Site:
S128
Identified Species:
69.05
UniProt:
P11766
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11766
NP_000662.3
374
39724
S128
G
L
M
P
D
G
T
S
R
F
T
C
K
G
K
Chimpanzee
Pan troglodytes
Q5R1W2
375
39808
R129
G
T
L
Q
D
G
T
R
R
F
T
C
R
G
K
Rhesus Macaque
Macaca mulatta
P28469
375
39894
S129
G
T
L
Q
D
G
T
S
R
F
T
C
R
G
K
Dog
Lupus familis
XP_532181
374
39645
S128
G
L
M
P
D
G
T
S
R
F
T
C
K
G
K
Cat
Felis silvestris
Mouse
Mus musculus
P28474
374
39529
S128
G
L
M
P
D
G
T
S
R
F
T
C
K
G
K
Rat
Rattus norvegicus
P12711
374
39557
S128
G
L
M
P
D
G
T
S
R
F
T
C
K
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23991
376
39789
T129
T
G
L
M
A
D
G
T
T
R
F
T
C
K
G
Frog
Xenopus laevis
NP_001086427
376
39998
S130
G
F
M
P
D
G
T
S
R
F
T
C
K
G
Q
Zebra Danio
Brachydanio rerio
NP_571924
376
40014
S130
G
L
M
P
D
N
T
S
R
F
T
C
K
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46415
379
40371
S131
G
V
M
P
E
G
T
S
R
L
S
C
K
G
Q
Honey Bee
Apis mellifera
XP_393266
377
40445
S131
G
V
M
P
D
G
T
S
R
F
T
C
K
G
Q
Nematode Worm
Caenorhab. elegans
Q17335
384
41274
S131
G
F
M
P
D
G
S
S
R
F
T
C
N
G
K
Sea Urchin
Strong. purpuratus
XP_784441
377
40249
S131
G
V
M
P
D
G
T
S
R
F
T
C
K
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P93629
381
40753
K132
G
V
M
M
N
D
M
K
S
R
F
S
V
N
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96533
379
40680
K130
G
I
M
M
N
D
R
K
S
R
F
S
V
N
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
60.7
94.9
N.A.
93
94.3
N.A.
N.A.
63.5
86.1
80.8
N.A.
71.2
74
68.2
70
Protein Similarity:
100
78.1
76.8
98.9
N.A.
98.1
98.1
N.A.
N.A.
78.9
94.4
90.9
N.A.
83.6
86.7
81.2
83.5
P-Site Identity:
100
66.6
73.3
100
N.A.
100
100
N.A.
N.A.
0
86.6
93.3
N.A.
66.6
86.6
80
93.3
P-Site Similarity:
100
80
86.6
100
N.A.
100
100
N.A.
N.A.
13.3
93.3
93.3
N.A.
93.3
100
86.6
100
Percent
Protein Identity:
N.A.
65.3
N.A.
68
N.A.
N.A.
Protein Similarity:
N.A.
78.2
N.A.
80.2
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
80
7
0
0
% C
% Asp:
0
0
0
0
74
20
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
14
0
0
0
0
0
0
0
74
20
0
0
0
0
% F
% Gly:
94
7
0
0
0
74
7
0
0
0
0
0
0
80
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
14
0
0
0
0
60
7
60
% K
% Leu:
0
34
20
0
0
0
0
0
0
7
0
0
0
0
0
% L
% Met:
0
0
80
20
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
14
7
0
0
0
0
0
0
7
14
0
% N
% Pro:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
14
0
0
0
0
0
0
0
0
0
0
20
% Q
% Arg:
0
0
0
0
0
0
7
7
80
20
0
0
14
0
0
% R
% Ser:
0
0
0
0
0
0
7
74
14
0
7
14
0
0
0
% S
% Thr:
7
14
0
0
0
0
74
7
7
0
74
7
0
0
0
% T
% Val:
0
27
0
0
0
0
0
0
0
0
0
0
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _