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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADH5
All Species:
16.97
Human Site:
S247
Identified Species:
26.67
UniProt:
P11766
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11766
NP_000662.3
374
39724
S247
C
I
N
P
Q
D
F
S
K
P
I
Q
E
V
L
Chimpanzee
Pan troglodytes
Q5R1W2
375
39808
K248
C
I
N
P
Q
D
Y
K
K
P
I
Q
E
V
L
Rhesus Macaque
Macaca mulatta
P28469
375
39894
K248
C
I
N
P
Q
D
Y
K
K
P
I
Q
E
V
L
Dog
Lupus familis
XP_532181
374
39645
S247
C
I
N
P
Q
D
F
S
K
P
I
Q
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P28474
374
39529
S247
C
I
S
P
Q
D
F
S
K
S
I
Q
E
V
L
Rat
Rattus norvegicus
P12711
374
39557
S247
C
I
N
P
Q
D
F
S
K
S
I
Q
E
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23991
376
39789
K249
C
I
N
P
K
D
F
K
K
P
I
H
E
V
L
Frog
Xenopus laevis
NP_001086427
376
39998
N249
C
L
N
P
A
D
F
N
K
P
I
Q
D
V
L
Zebra Danio
Brachydanio rerio
NP_571924
376
40014
S249
F
V
N
P
K
D
H
S
K
P
I
Q
E
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46415
379
40371
K252
N
P
K
D
V
A
D
K
G
S
I
Q
N
Y
L
Honey Bee
Apis mellifera
XP_393266
377
40445
N250
F
I
N
P
K
D
Y
N
K
P
I
Q
E
V
L
Nematode Worm
Caenorhab. elegans
Q17335
384
41274
G254
K
S
V
E
L
P
E
G
K
S
F
Q
A
W
L
Sea Urchin
Strong. purpuratus
XP_784441
377
40249
D250
F
V
N
P
K
T
L
D
K
P
T
Q
Q
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P93629
381
40753
D252
F
V
N
P
K
E
H
D
K
P
I
Q
Q
V
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96533
379
40680
D250
F
V
N
P
K
D
H
D
K
P
I
Q
E
V
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
60.7
94.9
N.A.
93
94.3
N.A.
N.A.
63.5
86.1
80.8
N.A.
71.2
74
68.2
70
Protein Similarity:
100
78.1
76.8
98.9
N.A.
98.1
98.1
N.A.
N.A.
78.9
94.4
90.9
N.A.
83.6
86.7
81.2
83.5
P-Site Identity:
100
86.6
86.6
100
N.A.
86.6
93.3
N.A.
N.A.
80
73.3
73.3
N.A.
20
73.3
20
40
P-Site Similarity:
100
93.3
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
86.6
93.3
86.6
N.A.
20
93.3
20
60
Percent
Protein Identity:
N.A.
65.3
N.A.
68
N.A.
N.A.
Protein Similarity:
N.A.
78.2
N.A.
80.2
N.A.
N.A.
P-Site Identity:
N.A.
53.3
N.A.
60
N.A.
N.A.
P-Site Similarity:
N.A.
80
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
0
0
0
0
7
7
0
% A
% Cys:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
74
7
20
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
7
0
7
7
0
0
0
0
0
67
0
0
% E
% Phe:
34
0
0
0
0
0
40
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
7
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
20
0
0
0
0
7
0
0
0
% H
% Ile:
0
54
0
0
0
0
0
0
0
0
87
0
0
0
7
% I
% Lys:
7
0
7
0
40
0
0
27
94
0
0
0
0
0
0
% K
% Leu:
0
7
0
0
7
0
7
0
0
0
0
0
0
0
94
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
80
0
0
0
0
14
0
0
0
0
7
0
0
% N
% Pro:
0
7
0
87
0
7
0
0
0
74
0
0
0
0
0
% P
% Gln:
0
0
0
0
40
0
0
0
0
0
0
94
14
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
7
0
0
0
0
34
0
27
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% T
% Val:
0
27
7
0
7
0
0
0
0
0
0
0
0
80
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _