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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADH5
All Species:
18.18
Human Site:
S333
Identified Species:
28.57
UniProt:
P11766
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11766
NP_000662.3
374
39724
S333
E
S
V
P
K
L
V
S
E
Y
M
S
K
K
I
Chimpanzee
Pan troglodytes
Q5R1W2
375
39808
A334
E
G
I
P
K
L
V
A
D
F
M
A
K
K
F
Rhesus Macaque
Macaca mulatta
P28469
375
39894
A334
E
D
I
P
K
L
V
A
D
F
M
A
K
K
F
Dog
Lupus familis
XP_532181
374
39645
S333
E
S
V
P
K
L
V
S
E
Y
M
S
R
K
I
Cat
Felis silvestris
Mouse
Mus musculus
P28474
374
39529
S333
E
S
V
P
K
L
V
S
E
Y
M
S
K
K
I
Rat
Rattus norvegicus
P12711
374
39557
S333
E
S
V
P
K
L
V
S
E
Y
M
S
K
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23991
376
39789
A335
D
A
V
P
K
L
V
A
D
Y
M
K
K
K
F
Frog
Xenopus laevis
NP_001086427
376
39998
S335
D
S
V
P
K
L
V
S
E
Y
M
A
K
K
I
Zebra Danio
Brachydanio rerio
NP_571924
376
40014
N335
E
S
V
P
K
L
V
N
D
Y
M
N
K
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46415
379
40371
E338
S
D
V
P
K
L
V
E
D
Y
L
K
K
D
L
Honey Bee
Apis mellifera
XP_393266
377
40445
K336
E
S
V
P
K
L
V
K
E
Y
M
S
K
S
L
Nematode Worm
Caenorhab. elegans
Q17335
384
41274
D340
E
S
V
P
R
L
V
D
D
Y
M
N
K
K
L
Sea Urchin
Strong. purpuratus
XP_784441
377
40249
E336
D
G
V
P
Q
L
V
E
E
Y
L
A
G
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P93629
381
40753
D338
T
Q
V
P
W
L
V
D
K
Y
M
K
K
E
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96533
379
40680
E336
T
Q
V
P
W
L
V
E
K
Y
M
N
K
E
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
60.7
94.9
N.A.
93
94.3
N.A.
N.A.
63.5
86.1
80.8
N.A.
71.2
74
68.2
70
Protein Similarity:
100
78.1
76.8
98.9
N.A.
98.1
98.1
N.A.
N.A.
78.9
94.4
90.9
N.A.
83.6
86.7
81.2
83.5
P-Site Identity:
100
53.3
53.3
93.3
N.A.
100
100
N.A.
N.A.
60
86.6
73.3
N.A.
46.6
80
66.6
40
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
100
N.A.
N.A.
86.6
100
100
N.A.
66.6
86.6
93.3
73.3
Percent
Protein Identity:
N.A.
65.3
N.A.
68
N.A.
N.A.
Protein Similarity:
N.A.
78.2
N.A.
80.2
N.A.
N.A.
P-Site Identity:
N.A.
53.3
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
20
0
0
0
27
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
14
0
0
0
0
0
14
40
0
0
0
0
7
0
% D
% Glu:
60
0
0
0
0
0
0
20
47
0
0
0
0
14
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
20
% F
% Gly:
0
14
0
0
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
47
% I
% Lys:
0
0
0
0
74
0
0
7
14
0
0
20
87
67
0
% K
% Leu:
0
0
0
0
0
100
0
0
0
0
14
0
0
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
87
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
0
0
20
0
0
0
% N
% Pro:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
14
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% R
% Ser:
7
54
0
0
0
0
0
34
0
0
0
34
0
7
0
% S
% Thr:
14
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% T
% Val:
0
0
87
0
0
0
100
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
14
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
87
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _