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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADH5
All Species:
43.03
Human Site:
S53
Identified Species:
67.62
UniProt:
P11766
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11766
NP_000662.3
374
39724
S53
H
T
D
A
Y
T
L
S
G
A
D
P
E
G
C
Chimpanzee
Pan troglodytes
Q5R1W2
375
39808
S55
R
T
D
D
H
V
V
S
G
N
L
V
T
P
L
Rhesus Macaque
Macaca mulatta
P28469
375
39894
S55
G
T
D
D
H
V
V
S
G
T
M
V
T
P
L
Dog
Lupus familis
XP_532181
374
39645
S53
H
T
D
A
Y
T
L
S
G
A
D
P
E
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P28474
374
39529
S53
H
T
D
A
Y
T
L
S
G
A
D
P
E
G
C
Rat
Rattus norvegicus
P12711
374
39557
S53
H
T
D
A
Y
T
L
S
G
A
D
P
E
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23991
376
39789
T55
R
S
D
D
H
V
V
T
G
A
L
A
M
P
F
Frog
Xenopus laevis
NP_001086427
376
39998
S55
H
T
D
A
Y
T
L
S
G
A
D
P
E
G
C
Zebra Danio
Brachydanio rerio
NP_571924
376
40014
S55
H
T
D
A
Y
T
L
S
G
S
D
P
E
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46415
379
40371
S56
H
T
D
A
F
T
L
S
G
A
D
P
E
G
L
Honey Bee
Apis mellifera
XP_393266
377
40445
D56
H
T
D
A
Y
T
L
D
G
L
D
P
E
G
I
Nematode Worm
Caenorhab. elegans
Q17335
384
41274
D56
H
T
D
A
Y
T
L
D
G
H
D
P
E
G
L
Sea Urchin
Strong. purpuratus
XP_784441
377
40249
S56
H
T
D
A
Y
T
L
S
G
A
D
S
E
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P93629
381
40753
S57
H
T
D
H
Y
T
W
S
G
K
D
P
E
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96533
379
40680
S55
H
T
D
A
Y
T
W
S
G
K
D
P
E
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
60.7
94.9
N.A.
93
94.3
N.A.
N.A.
63.5
86.1
80.8
N.A.
71.2
74
68.2
70
Protein Similarity:
100
78.1
76.8
98.9
N.A.
98.1
98.1
N.A.
N.A.
78.9
94.4
90.9
N.A.
83.6
86.7
81.2
83.5
P-Site Identity:
100
26.6
26.6
93.3
N.A.
100
100
N.A.
N.A.
20
100
86.6
N.A.
86.6
80
80
86.6
P-Site Similarity:
100
40
40
93.3
N.A.
100
100
N.A.
N.A.
46.6
100
93.3
N.A.
93.3
80
80
86.6
Percent
Protein Identity:
N.A.
65.3
N.A.
68
N.A.
N.A.
Protein Similarity:
N.A.
78.2
N.A.
80.2
N.A.
N.A.
P-Site Identity:
N.A.
73.3
N.A.
80
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
74
0
0
0
0
0
54
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
27
% C
% Asp:
0
0
100
20
0
0
0
14
0
0
80
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% E
% Phe:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
7
0
0
0
0
0
0
0
100
0
0
0
0
80
0
% G
% His:
80
0
0
7
20
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
7
% K
% Leu:
0
0
0
0
0
0
67
0
0
7
14
0
0
0
47
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
74
0
20
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
7
0
0
0
0
0
80
0
7
0
7
0
0
7
% S
% Thr:
0
94
0
0
0
80
0
7
0
7
0
0
14
0
0
% T
% Val:
0
0
0
0
0
20
20
0
0
0
0
14
0
0
0
% V
% Trp:
0
0
0
0
0
0
14
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
74
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _