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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADH5
All Species:
44.55
Human Site:
T238
Identified Species:
70
UniProt:
P11766
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11766
NP_000662.3
374
39724
T238
R
A
K
E
F
G
A
T
E
C
I
N
P
Q
D
Chimpanzee
Pan troglodytes
Q5R1W2
375
39808
T239
K
A
K
E
L
G
A
T
E
C
I
N
P
Q
D
Rhesus Macaque
Macaca mulatta
P28469
375
39894
T239
K
A
K
E
L
G
A
T
E
C
I
N
P
Q
D
Dog
Lupus familis
XP_532181
374
39645
S238
R
A
K
E
F
G
A
S
E
C
I
N
P
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
P28474
374
39529
S238
K
A
K
E
F
G
A
S
E
C
I
S
P
Q
D
Rat
Rattus norvegicus
P12711
374
39557
T238
K
A
K
E
F
G
A
T
E
C
I
N
P
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23991
376
39789
T240
K
A
K
E
L
G
A
T
E
C
I
N
P
K
D
Frog
Xenopus laevis
NP_001086427
376
39998
T240
K
A
T
E
F
G
A
T
E
C
L
N
P
A
D
Zebra Danio
Brachydanio rerio
NP_571924
376
40014
T240
I
A
K
K
F
G
A
T
E
F
V
N
P
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46415
379
40371
F243
K
K
F
G
F
T
D
F
V
N
P
K
D
V
A
Honey Bee
Apis mellifera
XP_393266
377
40445
T241
V
A
K
K
F
G
C
T
E
F
I
N
P
K
D
Nematode Worm
Caenorhab. elegans
Q17335
384
41274
N245
F
G
A
T
E
C
I
N
P
K
S
V
E
L
P
Sea Urchin
Strong. purpuratus
XP_784441
377
40249
T241
L
A
R
Q
F
G
A
T
H
F
V
N
P
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P93629
381
40753
T243
V
A
K
N
F
G
V
T
E
F
V
N
P
K
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96533
379
40680
N241
T
A
K
K
F
G
V
N
E
F
V
N
P
K
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
60.7
94.9
N.A.
93
94.3
N.A.
N.A.
63.5
86.1
80.8
N.A.
71.2
74
68.2
70
Protein Similarity:
100
78.1
76.8
98.9
N.A.
98.1
98.1
N.A.
N.A.
78.9
94.4
90.9
N.A.
83.6
86.7
81.2
83.5
P-Site Identity:
100
86.6
86.6
93.3
N.A.
80
93.3
N.A.
N.A.
80
73.3
66.6
N.A.
6.6
66.6
0
46.6
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
N.A.
93.3
86.6
86.6
N.A.
13.3
80
0
73.3
Percent
Protein Identity:
N.A.
65.3
N.A.
68
N.A.
N.A.
Protein Similarity:
N.A.
78.2
N.A.
80.2
N.A.
N.A.
P-Site Identity:
N.A.
53.3
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
73.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
87
7
0
0
0
67
0
0
0
0
0
0
7
7
% A
% Cys:
0
0
0
0
0
7
7
0
0
54
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
74
% D
% Glu:
0
0
0
54
7
0
0
0
80
0
0
0
7
0
7
% E
% Phe:
7
0
7
0
74
0
0
7
0
34
0
0
0
0
0
% F
% Gly:
0
7
0
7
0
87
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
7
0
0
0
54
0
0
0
0
% I
% Lys:
47
7
74
20
0
0
0
0
0
7
0
7
0
40
0
% K
% Leu:
7
0
0
0
20
0
0
0
0
0
7
0
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
14
0
7
0
80
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
7
0
87
0
7
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
40
0
% Q
% Arg:
14
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
14
0
0
7
7
0
0
0
% S
% Thr:
7
0
7
7
0
7
0
67
0
0
0
0
0
0
7
% T
% Val:
14
0
0
0
0
0
14
0
7
0
27
7
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _