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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADH5 All Species: 52.12
Human Site: T317 Identified Species: 81.9
UniProt: P11766 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11766 NP_000662.3 374 39724 T317 T G R T W K G T A F G G W K S
Chimpanzee Pan troglodytes Q5R1W2 375 39808 A318 T G R T W K G A V Y G G F K S
Rhesus Macaque Macaca mulatta P28469 375 39894 A318 T G R T W K G A V Y G G F K S
Dog Lupus familis XP_532181 374 39645 T317 T G R V W K G T A F G G W K S
Cat Felis silvestris
Mouse Mus musculus P28474 374 39529 T317 T G R T W K G T A F G G W K S
Rat Rattus norvegicus P12711 374 39557 T317 T G R T W K G T A F G G W K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P23991 376 39789 S319 S G R T W K G S V F G G W K S
Frog Xenopus laevis NP_001086427 376 39998 T319 T G R V W K G T A F G G W K S
Zebra Danio Brachydanio rerio NP_571924 376 40014 T319 T G R T W K G T A F G G W K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46415 379 40371 S322 V G R V W K G S A F G G W R S
Honey Bee Apis mellifera XP_393266 377 40445 T320 T G R V W K G T A F G G W K S
Nematode Worm Caenorhab. elegans Q17335 384 41274 T324 T G R T W K G T A F G G W K S
Sea Urchin Strong. purpuratus XP_784441 377 40249 T320 T G R T W K G T A F G G Y K S
Poplar Tree Populus trichocarpa
Maize Zea mays P93629 381 40753 T322 T G R V W K G T A F G G F K S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96533 379 40680 T320 T G R V W K G T A F G G F K S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 62.1 60.7 94.9 N.A. 93 94.3 N.A. N.A. 63.5 86.1 80.8 N.A. 71.2 74 68.2 70
Protein Similarity: 100 78.1 76.8 98.9 N.A. 98.1 98.1 N.A. N.A. 78.9 94.4 90.9 N.A. 83.6 86.7 81.2 83.5
P-Site Identity: 100 73.3 73.3 93.3 N.A. 100 100 N.A. N.A. 80 93.3 100 N.A. 73.3 93.3 100 93.3
P-Site Similarity: 100 86.6 86.6 93.3 N.A. 100 100 N.A. N.A. 93.3 93.3 100 N.A. 86.6 93.3 100 100
Percent
Protein Identity: N.A. 65.3 N.A. 68 N.A. N.A.
Protein Similarity: N.A. 78.2 N.A. 80.2 N.A. N.A.
P-Site Identity: N.A. 86.6 N.A. 86.6 N.A. N.A.
P-Site Similarity: N.A. 93.3 N.A. 93.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 14 80 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 87 0 0 27 0 0 % F
% Gly: 0 100 0 0 0 0 100 0 0 0 100 100 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 100 0 0 0 0 0 0 0 94 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 100 0 0 0 0 0 0 0 0 0 0 7 0 % R
% Ser: 7 0 0 0 0 0 0 14 0 0 0 0 0 0 100 % S
% Thr: 87 0 0 60 0 0 0 74 0 0 0 0 0 0 0 % T
% Val: 7 0 0 40 0 0 0 0 20 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 100 0 0 0 0 0 0 0 67 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 14 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _