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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADH5
All Species:
34.47
Human Site:
T370
Identified Species:
54.17
UniProt:
P11766
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11766
NP_000662.3
374
39724
T370
H
S
G
K
S
I
R
T
V
V
K
I
_
_
_
Chimpanzee
Pan troglodytes
Q5R1W2
375
39808
T371
H
S
G
K
S
I
R
T
V
L
T
F
_
_
_
Rhesus Macaque
Macaca mulatta
P28469
375
39894
T371
R
S
G
K
S
I
R
T
I
L
T
F
_
_
_
Dog
Lupus familis
XP_532181
374
39645
T370
H
A
G
K
S
I
R
T
V
V
K
L
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P28474
374
39529
T370
H
S
G
D
S
I
R
T
V
L
K
M
_
_
_
Rat
Rattus norvegicus
P12711
374
39557
T370
H
S
G
N
S
I
R
T
V
L
K
M
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23991
376
39789
S372
R
T
G
K
S
I
R
S
V
L
V
L
_
_
_
Frog
Xenopus laevis
NP_001086427
376
39998
S372
H
A
G
K
S
I
R
S
V
L
N
Y
_
_
_
Zebra Danio
Brachydanio rerio
NP_571924
376
40014
A372
H
A
G
K
S
I
R
A
V
L
Q
F
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46415
379
40371
S375
H
K
G
E
S
I
R
S
I
I
K
Y
_
_
_
Honey Bee
Apis mellifera
XP_393266
377
40445
A373
H
S
G
N
C
L
R
A
V
L
K
Y
_
_
_
Nematode Worm
Caenorhab. elegans
Q17335
384
41274
S377
H
K
G
E
S
L
R
S
V
L
A
F
E
K
I
Sea Urchin
Strong. purpuratus
XP_784441
377
40249
A373
H
D
G
E
S
I
R
A
I
V
N
F
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P93629
381
40753
C375
H
E
G
G
C
L
R
C
V
L
A
M
Q
I
_
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96533
379
40680
C373
H
E
G
T
C
L
R
C
V
L
D
T
S
K
_
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
60.7
94.9
N.A.
93
94.3
N.A.
N.A.
63.5
86.1
80.8
N.A.
71.2
74
68.2
70
Protein Similarity:
100
78.1
76.8
98.9
N.A.
98.1
98.1
N.A.
N.A.
78.9
94.4
90.9
N.A.
83.6
86.7
81.2
83.5
P-Site Identity:
100
75
58.3
83.3
N.A.
75
75
N.A.
N.A.
50
58.3
58.3
N.A.
50
50
33.3
50
P-Site Similarity:
100
83.3
75
100
N.A.
91.6
91.6
N.A.
N.A.
83.3
83.3
83.3
N.A.
83.3
66.6
66.6
66.6
Percent
Protein Identity:
N.A.
65.3
N.A.
68
N.A.
N.A.
Protein Similarity:
N.A.
78.2
N.A.
80.2
N.A.
N.A.
P-Site Identity:
N.A.
28.5
N.A.
28.5
N.A.
N.A.
P-Site Similarity:
N.A.
57.1
N.A.
42.8
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
0
0
20
0
0
14
0
0
0
0
% A
% Cys:
0
0
0
0
20
0
0
14
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
14
0
20
0
0
0
0
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% F
% Gly:
0
0
100
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
87
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
74
0
0
20
7
0
7
0
7
7
% I
% Lys:
0
14
0
47
0
0
0
0
0
0
40
0
0
14
0
% K
% Leu:
0
0
0
0
0
27
0
0
0
74
0
14
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% M
% Asn:
0
0
0
14
0
0
0
0
0
0
14
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
7
0
0
% Q
% Arg:
14
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% R
% Ser:
0
40
0
0
80
0
0
27
0
0
0
0
7
0
0
% S
% Thr:
0
7
0
7
0
0
0
40
0
0
14
7
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
80
20
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
80
80
94
% _