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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADH5
All Species:
4.55
Human Site:
Y140
Identified Species:
7.14
UniProt:
P11766
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11766
NP_000662.3
374
39724
Y140
K
G
K
T
I
L
H
Y
M
G
T
S
T
F
S
Chimpanzee
Pan troglodytes
Q5R1W2
375
39808
F141
R
G
K
P
I
H
H
F
L
G
T
S
T
F
S
Rhesus Macaque
Macaca mulatta
P28469
375
39894
F141
R
G
K
P
I
H
H
F
L
G
V
S
T
F
S
Dog
Lupus familis
XP_532181
374
39645
Y140
K
G
K
T
I
L
H
Y
M
G
T
S
T
F
S
Cat
Felis silvestris
Mouse
Mus musculus
P28474
374
39529
F140
K
G
K
S
V
F
H
F
M
G
T
S
T
F
S
Rat
Rattus norvegicus
P12711
374
39557
F140
K
G
K
P
I
L
H
F
M
G
T
S
T
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P23991
376
39789
H141
C
K
G
K
A
I
H
H
F
V
G
T
S
T
F
Frog
Xenopus laevis
NP_001086427
376
39998
F142
K
G
Q
Q
I
F
H
F
M
G
T
S
T
F
S
Zebra Danio
Brachydanio rerio
NP_571924
376
40014
F142
K
G
K
Q
L
F
H
F
M
G
T
S
T
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46415
379
40371
F143
K
G
Q
Q
L
F
H
F
M
G
T
S
T
F
A
Honey Bee
Apis mellifera
XP_393266
377
40445
F143
K
G
Q
T
L
A
H
F
M
G
C
S
T
F
S
Nematode Worm
Caenorhab. elegans
Q17335
384
41274
F143
N
G
K
Q
L
F
H
F
M
G
C
S
T
F
S
Sea Urchin
Strong. purpuratus
XP_784441
377
40249
F143
K
G
K
T
L
Y
H
F
M
G
T
S
T
F
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P93629
381
40753
H144
V
N
G
K
P
I
Y
H
F
M
G
T
S
T
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96533
379
40680
H142
V
N
G
K
P
I
Y
H
F
M
G
T
S
T
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.1
60.7
94.9
N.A.
93
94.3
N.A.
N.A.
63.5
86.1
80.8
N.A.
71.2
74
68.2
70
Protein Similarity:
100
78.1
76.8
98.9
N.A.
98.1
98.1
N.A.
N.A.
78.9
94.4
90.9
N.A.
83.6
86.7
81.2
83.5
P-Site Identity:
100
66.6
60
100
N.A.
73.3
86.6
N.A.
N.A.
6.6
73.3
73.3
N.A.
60
66.6
60
80
P-Site Similarity:
100
86.6
80
100
N.A.
93.3
93.3
N.A.
N.A.
33.3
86.6
86.6
N.A.
86.6
86.6
73.3
93.3
Percent
Protein Identity:
N.A.
65.3
N.A.
68
N.A.
N.A.
Protein Similarity:
N.A.
78.2
N.A.
80.2
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
14
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
34
0
67
20
0
0
0
0
80
20
% F
% Gly:
0
80
20
0
0
0
0
0
0
80
20
0
0
0
0
% G
% His:
0
0
0
0
0
14
87
20
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
40
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
60
7
60
20
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
34
20
0
0
14
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
67
14
0
0
0
0
0
% M
% Asn:
7
14
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
20
14
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
20
27
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
0
0
0
0
0
0
0
80
20
0
74
% S
% Thr:
0
0
0
27
0
0
0
0
0
0
60
20
80
20
0
% T
% Val:
14
0
0
0
7
0
0
0
0
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
14
14
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _