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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK4
All Species:
35.45
Human Site:
Y103
Identified Species:
70.91
UniProt:
P11802
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11802
NP_000066.1
303
33730
Y103
V
D
Q
D
L
R
T
Y
L
D
K
A
P
P
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116412
303
33725
Y103
V
D
Q
D
L
R
T
Y
L
D
K
A
P
P
P
Dog
Lupus familis
XP_538252
303
33686
Y103
V
D
Q
D
L
R
T
Y
L
D
K
A
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P30285
303
33732
Y103
I
D
Q
D
L
R
T
Y
L
D
K
A
P
P
P
Rat
Rattus norvegicus
P35426
303
33780
Y103
I
D
Q
D
L
R
T
Y
L
D
K
A
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001007893
326
36832
Y108
V
D
Q
D
L
T
T
Y
L
D
K
V
P
E
P
Frog
Xenopus laevis
Q91727
319
35666
Y103
V
D
Q
D
L
K
T
Y
L
S
K
V
P
P
P
Zebra Danio
Brachydanio rerio
NP_001071245
297
33310
Y103
V
D
Q
D
L
R
A
Y
L
E
K
V
P
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391955
457
50351
Y260
V
E
R
D
L
A
S
Y
M
S
S
C
S
Q
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999689
373
42086
Y109
V
D
Q
D
L
A
Q
Y
L
E
K
C
P
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P23111
294
33816
F90
L
D
L
D
L
K
K
F
M
D
S
C
P
E
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
H90
L
D
L
D
L
K
K
H
M
D
S
T
P
D
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
97
N.A.
94.7
95
N.A.
N.A.
65.3
72
71.9
N.A.
N.A.
35.2
N.A.
48.7
Protein Similarity:
100
N.A.
99.6
97.6
N.A.
97
97.3
N.A.
N.A.
75.7
79.9
80.1
N.A.
N.A.
50.3
N.A.
60.8
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
N.A.
80
80
73.3
N.A.
N.A.
26.6
N.A.
73.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
80
86.6
80
N.A.
N.A.
53.3
N.A.
80
Percent
Protein Identity:
N.A.
43.8
N.A.
45.5
N.A.
N.A.
Protein Similarity:
N.A.
62.7
N.A.
64
N.A.
N.A.
P-Site Identity:
N.A.
33.3
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
N.A.
60
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
9
0
0
0
0
42
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% C
% Asp:
0
92
0
100
0
0
0
0
0
67
0
0
0
9
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
17
0
0
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
17
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
25
17
0
0
0
75
0
0
0
0
% K
% Leu:
17
0
17
0
100
0
0
0
75
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
25
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
92
59
75
% P
% Gln:
0
0
75
0
0
0
9
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
9
0
0
50
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
0
0
17
25
0
9
0
0
% S
% Thr:
0
0
0
0
0
9
59
0
0
0
0
9
0
0
9
% T
% Val:
67
0
0
0
0
0
0
0
0
0
0
25
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _