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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRF
All Species:
25.76
Human Site:
S221
Identified Species:
40.48
UniProt:
P11831
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11831
NP_003122.1
508
51593
S221
L
I
Q
T
C
L
N
S
P
D
S
P
P
R
S
Chimpanzee
Pan troglodytes
XP_518487
508
51590
S221
L
I
Q
T
C
L
N
S
P
D
S
P
P
R
S
Rhesus Macaque
Macaca mulatta
XP_001093365
508
51688
S221
L
I
Q
T
C
L
N
S
P
D
S
P
P
R
S
Dog
Lupus familis
XP_852302
508
51510
S221
L
I
Q
T
C
L
N
S
P
D
S
P
P
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JM73
504
51229
S217
L
I
Q
T
C
L
N
S
P
D
S
P
P
R
S
Rat
Rattus norvegicus
NP_001102772
504
51157
S217
L
I
Q
T
C
L
N
S
P
D
S
P
P
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517936
150
15822
Chicken
Gallus gallus
Q90718
375
39146
Q101
R
S
D
P
T
T
D
Q
R
M
S
A
T
G
F
Frog
Xenopus laevis
P23790
448
46097
L174
K
A
L
I
Q
T
C
L
N
S
P
D
S
P
P
Zebra Danio
Brachydanio rerio
NP_001103996
539
55032
P209
D
S
P
P
R
T
D
P
S
T
D
Q
R
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24535
449
47603
Y174
R
V
K
I
K
M
E
Y
I
D
N
K
L
R
R
Honey Bee
Apis mellifera
XP_001120126
351
36852
S76
R
G
I
K
R
T
T
S
D
V
C
Y
D
D
S
Nematode Worm
Caenorhab. elegans
NP_492296
327
35027
E53
G
R
V
K
I
K
M
E
Y
I
N
N
K
L
R
Sea Urchin
Strong. purpuratus
XP_796790
410
43027
T136
G
H
V
Y
T
F
A
T
R
K
L
Q
P
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11746
286
32783
N12
E
E
G
T
P
T
N
N
G
Q
Q
K
E
R
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.4
97.2
N.A.
96.4
96.6
N.A.
22.8
66.5
72.4
57.7
N.A.
35
33.4
28.7
33.8
Protein Similarity:
100
99.8
98.8
98
N.A.
97.4
97.6
N.A.
24
69.6
76.9
67.7
N.A.
48.8
40.3
41.1
45.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
6.6
0
6.6
N.A.
13.3
13.3
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
13.3
0
13.3
N.A.
40
13.3
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
40
0
7
0
0
0
7
0
0
0
0
% C
% Asp:
7
0
7
0
0
0
14
0
7
47
7
7
7
7
0
% D
% Glu:
7
7
0
0
0
0
7
7
0
0
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
7
% F
% Gly:
14
7
7
0
0
0
0
0
7
0
0
0
0
7
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
40
7
14
7
0
0
0
7
7
0
0
0
0
7
% I
% Lys:
7
0
7
14
7
7
0
0
0
7
0
14
7
0
0
% K
% Leu:
40
0
7
0
0
40
0
7
0
0
7
0
7
7
0
% L
% Met:
0
0
0
0
0
7
7
0
0
7
0
0
0
14
0
% M
% Asn:
0
0
0
0
0
0
47
7
7
0
14
7
0
0
0
% N
% Pro:
0
0
7
14
7
0
0
7
40
0
7
40
47
7
7
% P
% Gln:
0
0
40
0
7
0
0
7
0
7
7
14
0
0
0
% Q
% Arg:
20
7
0
0
14
0
0
0
14
0
0
0
7
54
20
% R
% Ser:
0
14
0
0
0
0
0
47
7
7
47
0
7
0
54
% S
% Thr:
0
0
0
47
14
34
7
7
0
7
0
0
7
0
0
% T
% Val:
0
7
14
0
0
0
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
7
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _