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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRF All Species: 29.39
Human Site: S372 Identified Species: 46.19
UniProt: P11831 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11831 NP_003122.1 508 51593 S372 A P Q Q A S P S R D S S T D L
Chimpanzee Pan troglodytes XP_518487 508 51590 S372 A P Q Q A S P S R D S S T D L
Rhesus Macaque Macaca mulatta XP_001093365 508 51688 S372 A P Q Q G S P S R D S S T D L
Dog Lupus familis XP_852302 508 51510 S372 A P Q Q A S P S R D S S T D L
Cat Felis silvestris
Mouse Mus musculus Q9JM73 504 51229 S368 A P Q Q A S P S R D S S T D L
Rat Rattus norvegicus NP_001102772 504 51157 S368 A P Q Q A S P S R D S S T D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517936 150 15822 S16 Q A S P S S D S S S D L T Q T
Chicken Gallus gallus Q90718 375 39146 D241 Q Q T S P S S D S S T D L T Q
Frog Xenopus laevis P23790 448 46097 S314 V H S A A Q A S P S S D S S S
Zebra Danio Brachydanio rerio NP_001103996 539 55032 S405 Q V H P S P Q S S D S S P E I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24535 449 47603 T314 T K L P A S K T E V S A P P A
Honey Bee Apis mellifera XP_001120126 351 36852 S216 P D P P A S G S S G D Q R M S
Nematode Worm Caenorhab. elegans NP_492296 327 35027 D193 L F S T F G E D D Y N N D E S
Sea Urchin Strong. purpuratus XP_796790 410 43027 V276 L S A G M L Q V Q P S H S Q L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P11746 286 32783 Q152 L G H L N Q D Q V P A G A L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.4 97.2 N.A. 96.4 96.6 N.A. 22.8 66.5 72.4 57.7 N.A. 35 33.4 28.7 33.8
Protein Similarity: 100 99.8 98.8 98 N.A. 97.4 97.6 N.A. 24 69.6 76.9 67.7 N.A. 48.8 40.3 41.1 45.6
P-Site Identity: 100 100 93.3 100 N.A. 100 100 N.A. 20 6.6 20 26.6 N.A. 20 20 0 13.3
P-Site Similarity: 100 100 93.3 100 N.A. 100 100 N.A. 26.6 13.3 26.6 46.6 N.A. 33.3 20 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 7 7 7 54 0 7 0 0 0 7 7 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 0 14 14 7 47 14 14 7 40 0 % D
% Glu: 0 0 0 0 0 0 7 0 7 0 0 0 0 14 0 % E
% Phe: 0 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 7 0 7 7 7 7 0 0 7 0 7 0 0 0 % G
% His: 0 7 14 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % I
% Lys: 0 7 0 0 0 0 7 0 0 0 0 0 0 0 7 % K
% Leu: 20 0 7 7 0 7 0 0 0 0 0 7 7 7 47 % L
% Met: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 7 7 0 0 0 % N
% Pro: 7 40 7 27 7 7 40 0 7 14 0 0 14 7 0 % P
% Gln: 20 7 40 40 0 14 14 7 7 0 0 7 0 14 7 % Q
% Arg: 0 0 0 0 0 0 0 0 40 0 0 0 7 0 0 % R
% Ser: 0 7 20 7 14 67 7 67 27 20 67 47 14 7 20 % S
% Thr: 7 0 7 7 0 0 0 7 0 0 7 0 47 7 7 % T
% Val: 7 7 0 0 0 0 0 7 7 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _