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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRF All Species: 18.18
Human Site: Y76 Identified Species: 28.57
UniProt: P11831 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11831 NP_003122.1 508 51593 Y76 A P T A G A L Y S G S E G D S
Chimpanzee Pan troglodytes XP_518487 508 51590 Y76 A P T A G A L Y S G S E G D S
Rhesus Macaque Macaca mulatta XP_001093365 508 51688 Y76 A P T A G A L Y S G S E G D S
Dog Lupus familis XP_852302 508 51510 A77 T P A P T A G A L Y S G S E G
Cat Felis silvestris
Mouse Mus musculus Q9JM73 504 51229 Y72 A P T A G A L Y S G S E G D S
Rat Rattus norvegicus NP_001102772 504 51157 Y72 A P T A G A L Y S G S E G D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517936 150 15822
Chicken Gallus gallus Q90718 375 39146
Frog Xenopus laevis P23790 448 46097 G33 A G C P G I R G P G G Q Y S G
Zebra Danio Brachydanio rerio NP_001103996 539 55032 D65 S G S D G D S D S G D D E E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24535 449 47603 P33 P A D M Y G N P A L G A G R P
Honey Bee Apis mellifera XP_001120126 351 36852
Nematode Worm Caenorhab. elegans NP_492296 327 35027
Sea Urchin Strong. purpuratus XP_796790 410 43027
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P11746 286 32783
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.4 97.2 N.A. 96.4 96.6 N.A. 22.8 66.5 72.4 57.7 N.A. 35 33.4 28.7 33.8
Protein Similarity: 100 99.8 98.8 98 N.A. 97.4 97.6 N.A. 24 69.6 76.9 67.7 N.A. 48.8 40.3 41.1 45.6
P-Site Identity: 100 100 100 20 N.A. 100 100 N.A. 0 0 20 26.6 N.A. 6.6 0 0 0
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. 0 0 26.6 53.3 N.A. 13.3 0 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 7 7 34 0 40 0 7 7 0 0 7 0 0 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 7 0 7 0 7 0 0 7 7 0 34 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 34 7 14 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 14 0 0 47 7 7 7 0 47 14 7 40 0 14 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 34 0 7 7 0 0 0 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 7 40 0 14 0 0 0 7 7 0 0 0 0 0 7 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % R
% Ser: 7 0 7 0 0 0 7 0 40 0 40 0 7 7 40 % S
% Thr: 7 0 34 0 7 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 34 0 7 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _