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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPS2 All Species: 30.3
Human Site: S41 Identified Species: 60.61
UniProt: P11908 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11908 NP_001034180.1 318 34769 S41 K F S N Q E T S V E I G E S V
Chimpanzee Pan troglodytes XP_528013 318 34770 C41 K F S N Q E T C V E I D E S V
Rhesus Macaque Macaca mulatta XP_001105054 318 34745 C41 K F S N Q E T C V E I D E S V
Dog Lupus familis XP_856623 318 34775 S41 K F S N Q E T S V E I G E S V
Cat Felis silvestris
Mouse Mus musculus Q9CS42 318 34768 S41 K F S N Q E T S V E I G E S V
Rat Rattus norvegicus P09330 318 34795 S41 K F S N Q E T S V E I G E S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515197 594 64444 S317 L S T G G E T S V E I G E S V
Chicken Gallus gallus Q5ZI49 325 35645 S41 K F S N Q E T S V E I G E S V
Frog Xenopus laevis Q7ZXC9 318 34683 S41 K F S N Q E T S V E I G E S V
Zebra Danio Brachydanio rerio NP_001070036 318 34782 C41 K F S N Q E T C V E I G E S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648345 350 38261 C73 K F S N L E T C V E I G E S V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38063 327 35828 S51 Q Y S N K E T S V T I G E S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.5 92.4 99.3 N.A. 98.7 99 N.A. 51.8 95.6 96.8 94 N.A. 79.7 N.A. N.A. N.A.
Protein Similarity: 100 96.8 96.5 99.6 N.A. 99.6 99.6 N.A. 52.8 96.6 98.7 98.1 N.A. 85.4 N.A. N.A. N.A.
P-Site Identity: 100 86.6 86.6 100 N.A. 100 100 N.A. 66.6 100 100 93.3 N.A. 86.6 N.A. N.A. N.A.
P-Site Similarity: 100 86.6 86.6 100 N.A. 100 100 N.A. 73.3 100 100 93.3 N.A. 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 61.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 77.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 34 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % D
% Glu: 0 0 0 0 0 100 0 0 0 92 0 0 100 0 0 % E
% Phe: 0 84 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 9 9 0 0 0 0 0 0 84 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % I
% Lys: 84 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 75 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 92 0 0 0 0 67 0 0 0 0 0 100 0 % S
% Thr: 0 0 9 0 0 0 100 0 0 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 92 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _