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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPS2 All Species: 49.39
Human Site: Y311 Identified Species: 98.79
UniProt: P11908 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11908 NP_001034180.1 318 34769 Y311 H N G E S V S Y L F S H V P L
Chimpanzee Pan troglodytes XP_528013 318 34770 Y311 H N G E S V S Y L F S H V P L
Rhesus Macaque Macaca mulatta XP_001105054 318 34745 Y311 H N G E S V S Y L F S H V P L
Dog Lupus familis XP_856623 318 34775 Y311 H N G E S V S Y L F S H V P L
Cat Felis silvestris
Mouse Mus musculus Q9CS42 318 34768 Y311 H N G E S V S Y L F S H V P L
Rat Rattus norvegicus P09330 318 34795 Y311 H N G E S V S Y L F S H V P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515197 594 64444 Y587 H N G E S V S Y L F S H V P L
Chicken Gallus gallus Q5ZI49 325 35645 Y318 H N G E S V S Y L F S H V P L
Frog Xenopus laevis Q7ZXC9 318 34683 Y311 H N G E S V S Y L F S H V P L
Zebra Danio Brachydanio rerio NP_001070036 318 34782 Y311 H N G E S V S Y L F S H V P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648345 350 38261 Y343 H N G E S V S Y L F S N V P Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38063 327 35828 Y320 H N G E S V S Y L F T H A P V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.5 92.4 99.3 N.A. 98.7 99 N.A. 51.8 95.6 96.8 94 N.A. 79.7 N.A. N.A. N.A.
Protein Similarity: 100 96.8 96.5 99.6 N.A. 99.6 99.6 N.A. 52.8 96.6 98.7 98.1 N.A. 85.4 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 61.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 77.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 80 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % F
% Gly: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 100 0 0 0 0 0 0 0 0 0 0 92 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 84 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 100 0 0 0 0 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 100 0 100 0 0 0 92 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % T
% Val: 0 0 0 0 0 100 0 0 0 0 0 0 92 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _