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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PABPC1 All Species: 26.97
Human Site: Y422 Identified Species: 45.64
UniProt: P11940 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11940 NP_002559.2 636 70671 Y422 Q T Q N R A A Y Y P P S Q I A
Chimpanzee Pan troglodytes XP_001154541 633 70214 I422 A Y Y P P S Q I T Q L R P S P
Rhesus Macaque Macaca mulatta Q7JGR2 382 43298 N200 R D R A T F T N V F V K N I G
Dog Lupus familis XP_857417 636 70644 Y422 Q T Q N R A A Y Y P P S Q I A
Cat Felis silvestris
Mouse Mus musculus P29341 636 70624 Y422 Q T Q N R A A Y Y P P S Q I A
Rat Rattus norvegicus Q9EPH8 636 70682 Y422 Q T Q N R A A Y Y P P S Q I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509272 636 70681 Y422 Q T Q N R A A Y Y P A S Q I A
Chicken Gallus gallus NP_001026768 637 70922 Y422 Q T Q N R A A Y Y H T N Q L A
Frog Xenopus laevis Q6IP09 633 70403 P422 Q N R A A Y Y P P G Q I A Q L
Zebra Danio Brachydanio rerio NP_957176 634 71007 Y422 Q A Q N R A A Y Y P T S Q L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21187 634 69907 V416 Q R F F G S Q V A T Q M R N T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q05196 668 73191 N457 H P M F I G H N G Q G L V P S
Baker's Yeast Sacchar. cerevisiae P04147 577 64326 Y393 I V A G K P L Y V A I A Q R K
Red Bread Mold Neurospora crassa Q7S6N6 764 82299 G514 P G F M P A P G G R G V P F P
Conservation
Percent
Protein Identity: 100 92.1 38.2 98.9 N.A. 99.5 99.5 N.A. 99 97.8 94.3 91.8 N.A. 58.9 N.A. N.A. N.A.
Protein Similarity: 100 94.5 48.1 99 N.A. 100 99.8 N.A. 99.5 98.9 96.5 95.7 N.A. 72 N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 100 N.A. 100 100 N.A. 93.3 73.3 6.6 80 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 20 100 N.A. 100 100 N.A. 93.3 86.6 13.3 86.6 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 43.4 44.8 41.4
Protein Similarity: N.A. N.A. N.A. 58.8 59.4 54.5
P-Site Identity: N.A. N.A. N.A. 0 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 15 8 58 50 0 8 8 8 8 8 0 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 15 15 0 8 0 0 0 8 0 0 0 8 0 % F
% Gly: 0 8 0 8 8 8 0 8 15 8 15 0 0 0 8 % G
% His: 8 0 0 0 0 0 8 0 0 8 0 0 0 0 0 % H
% Ile: 8 0 0 0 8 0 0 8 0 0 8 8 0 43 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 8 % K
% Leu: 0 0 0 0 0 0 8 0 0 0 8 8 0 15 8 % L
% Met: 0 0 8 8 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 0 50 0 0 0 15 0 0 0 8 8 8 0 % N
% Pro: 8 8 0 8 15 8 8 8 8 43 29 0 15 8 15 % P
% Gln: 65 0 50 0 0 0 15 0 0 15 15 0 58 8 0 % Q
% Arg: 8 8 15 0 50 0 0 0 0 8 0 8 8 8 0 % R
% Ser: 0 0 0 0 0 15 0 0 0 0 0 43 0 8 8 % S
% Thr: 0 43 0 0 8 0 8 0 8 8 15 0 0 0 8 % T
% Val: 0 8 0 0 0 0 0 8 15 0 8 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 8 8 58 50 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _