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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGF5
All Species:
13.64
Human Site:
S222
Identified Species:
37.5
UniProt:
P12034
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12034
NP_004455.2
268
29551
S222
F
L
P
R
F
K
Q
S
E
Q
P
E
L
S
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089996
268
29617
S222
F
L
P
R
F
K
Q
S
E
Q
P
E
L
S
F
Dog
Lupus familis
XP_848478
207
22962
G162
I
Y
K
H
G
D
T
G
R
R
Y
F
V
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P15656
264
29085
K218
T
H
F
L
P
R
F
K
Q
S
E
Q
P
E
L
Rat
Rattus norvegicus
P48807
266
29246
S220
F
L
P
R
F
K
Q
S
E
Q
P
E
L
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505458
172
19227
S127
F
L
P
R
F
K
Q
S
E
P
P
E
L
S
F
Chicken
Gallus gallus
P48801
220
25031
Q175
G
F
K
T
R
R
T
Q
K
S
S
L
F
L
P
Frog
Xenopus laevis
Q91875
209
23644
Y164
A
D
T
G
R
R
Y
Y
V
A
L
N
K
D
G
Zebra Danio
Brachydanio rerio
P48802
256
28905
K211
L
P
R
V
L
A
N
K
D
H
E
M
V
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.7
30.9
N.A.
84.3
83.5
N.A.
55.2
28.7
32
34.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.2
45.5
N.A.
89.1
88.4
N.A.
59.7
43.6
44.7
50
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
0
100
N.A.
93.3
0
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
20
N.A.
20
100
N.A.
93.3
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
12
0
0
0
12
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
12
0
0
12
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
45
0
23
45
0
12
0
% E
% Phe:
45
12
12
0
45
0
12
0
0
0
0
12
12
0
45
% F
% Gly:
12
0
0
12
12
0
0
12
0
0
0
0
0
0
12
% G
% His:
0
12
0
12
0
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
23
0
0
45
0
23
12
0
0
0
12
0
12
% K
% Leu:
12
45
0
12
12
0
0
0
0
0
12
12
45
12
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% N
% Pro:
0
12
45
0
12
0
0
0
0
12
45
0
12
0
12
% P
% Gln:
0
0
0
0
0
0
45
12
12
34
0
12
0
0
0
% Q
% Arg:
0
0
12
45
23
34
0
0
12
12
0
0
0
12
0
% R
% Ser:
0
0
0
0
0
0
0
45
0
23
12
0
0
45
0
% S
% Thr:
12
0
12
12
0
0
23
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
12
0
0
0
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
12
12
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _